An observational study demonstrating the adherence and ease of
use of the injector device, RebiSmart (R)

J 2020

An observational study demonstrating the adherence and ease of use of the injector device, RebiSmart (R)

VALIS, Martin, Jana SARLAKOVA, Simona HALUSKOVA, Blanka KLIMOVA, Pavel POTUZNIK et. al.

Basic information

Original name

An observational study demonstrating the adherence and ease of use of the injector device, RebiSmart (R)

Authors

VALIS, Martin (203 Czech Republic), Jana SARLAKOVA (203 Czech Republic), Simona HALUSKOVA (203 Czech Republic), Blanka KLIMOVA (203 Czech Republic), Pavel POTUZNIK (203 Czech Republic), Marek PETERKA (203 Czech Republic), Kamil KUCA (203 Czech Republic), Pavel ŠTOURAČ (203 Czech Republic, belonging to the institution), Jan MARES (203 Czech Republic) and Zbysek PAVELEK (203 Czech Republic)

Edition

EXPERT OPINION ON DRUG DELIVERY, ABINGDON, TAYLOR & FRANCIS LTD, 2020, 1742-5247

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30104 Pharmacology and pharmacy

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 6.648

RIV identification code

RIV/00216224:14110/20:00116023

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1080/17425247.2020.1742694

UT WoS

000528167500001

Keywords in English

Multiple Sclerosis; patients; adherence; treatment; use; RebiSmart

Abstract

V originále

Background: Adherence to Multiple Sclerosis (MS) treatment is considered one of the crucial factors for ensuring optimal clinical outcomes. Research has shown that the use of self-injector devices improves patient compliance with treatment. Therefore, the main purpose of this study is to evaluate the ease of use of RebiSmart (R) 2.0 in clinically isolated syndrome/relapsing-remitting MS patients during 12 months treatment period. Methods: A total number of 290 subjects entered into data collection; 249 (86%) of them completed the whole 12 months study period. The primary endpoints and the secondary endpoints were assessed by the User Study Questionnaire. Adherence data were retrieved from RebiSmart (R) 2.0 (Menu - Dose History) on the respective patient's visit. Outcome measures also included Expanded Disability Status Score, Kurtzke Functional Systems, and Modified Social Support Survey, Modified Social Support Survey-5. Results: This study demonstrated a very high proportion (>95%) of patients with a positive rating of the overall ease of use and the overall convenience of RebiSmart (R). The proportion of patients with a positive rating of the ease of use by individual domains and the functions of RebiSmart (R) were also high (>80%). Conclusion: The findings demonstrate a very good perception of the usability of the device by patients overall and in its individual functions.

Citovat

VALIS, Martin, Jana SARLAKOVA, Simona HALUSKOVA, Blanka KLIMOVA, Pavel POTUZNIK, Marek PETERKA, Kamil KUCA, Pavel ŠTOURAČ, Jan MARES and Zbysek PAVELEK. An observational study demonstrating the adherence and ease of use of the injector device, RebiSmart (R). EXPERT OPINION ON DRUG DELIVERY. ABINGDON: TAYLOR & FRANCIS LTD, 2020, vol. 17, No 5, p. 719-724. ISSN 1742-5247. Available from: https://dx.doi.org/10.1080/17425247.2020.1742694.

@article{1670605,
   author = {Valis, Martin and Sarlakova, Jana and Haluskova, Simona and Klimova, Blanka and Potuznik, Pavel and Peterka, Marek and Kuca, Kamil and Štourač, Pavel and Mares, Jan and Pavelek, Zbysek},
   article_location = {ABINGDON},
   article_number = {5},
   doi = {http://dx.doi.org/10.1080/17425247.2020.1742694},
   keywords = {Multiple Sclerosis; patients; adherence; treatment; use; RebiSmart},
   language = {eng},
   issn = {1742-5247},
   journal = {EXPERT OPINION ON DRUG DELIVERY},
   title = {An observational study demonstrating the adherence and ease of use of the injector device, RebiSmart (R)},
   url = {https://www.tandfonline.com/doi/abs/10.1080/17425247.2020.1742694?journalCode=iedd20},
   volume = {17},
   year = {2020}
}

TY  - JOUR
ID  - 1670605
AU  - Valis, Martin - Sarlakova, Jana - Haluskova, Simona - Klimova, Blanka - Potuznik, Pavel - Peterka, Marek - Kuca, Kamil - Štourač, Pavel - Mares, Jan - Pavelek, Zbysek
PY  - 2020
TI  - An observational study demonstrating the adherence and ease of use of the injector device, RebiSmart (R)
JF  - EXPERT OPINION ON DRUG DELIVERY
VL  - 17
IS  - 5
SP  - 719-724
EP  - 719-724
PB  - TAYLOR & FRANCIS LTD
SN  - 17425247
KW  - Multiple Sclerosis
KW  - patients
KW  - adherence
KW  - treatment
KW  - use
KW  - RebiSmart
UR  - https://www.tandfonline.com/doi/abs/10.1080/17425247.2020.1742694?journalCode=iedd20
L2  - https://www.tandfonline.com/doi/abs/10.1080/17425247.2020.1742694?journalCode=iedd20
N2  - Background: Adherence to Multiple Sclerosis (MS) treatment is considered one of the crucial factors for ensuring optimal clinical outcomes. Research has shown that the use of self-injector devices improves patient compliance with treatment. Therefore, the main purpose of this study is to evaluate the ease of use of RebiSmart (R) 2.0 in clinically isolated syndrome/relapsing-remitting MS patients during 12 months treatment period. Methods: A total number of 290 subjects entered into data collection; 249 (86%) of them completed the whole 12 months study period. The primary endpoints and the secondary endpoints were assessed by the User Study Questionnaire. Adherence data were retrieved from RebiSmart (R) 2.0 (Menu - Dose History) on the respective patient's visit. Outcome measures also included Expanded Disability Status Score, Kurtzke Functional Systems, and Modified Social Support Survey, Modified Social Support Survey-5. Results: This study demonstrated a very high proportion (>95%) of patients with a positive rating of the overall ease of use and the overall convenience of RebiSmart (R). The proportion of patients with a positive rating of the ease of use by individual domains and the functions of RebiSmart (R) were also high (>80%). Conclusion: The findings demonstrate a very good perception of the usability of the device by patients overall and in its individual functions.
ER  -

VALIS, Martin, Jana SARLAKOVA, Simona HALUSKOVA, Blanka KLIMOVA, Pavel POTUZNIK, Marek PETERKA, Kamil KUCA, Pavel ŠTOURAČ, Jan MARES and Zbysek PAVELEK. An observational study demonstrating the adherence and ease of use of the injector device, RebiSmart (R). \textit{EXPERT OPINION ON DRUG DELIVERY}. ABINGDON: TAYLOR \&{} FRANCIS LTD, 2020, vol.~17, No~5, p.~719-724. ISSN~1742-5247. Available from: https://dx.doi.org/10.1080/17425247.2020.1742694.

Detailed Information on Publication Record