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@article{1670809,
author = {Jabandžiev, Petr and Jouza, Martin and Pecl, Jakub and Urík, Milan and Papež, Jan and Pinkasová, Tereza and Slabá, Kateřina and Trna, Jan and Kyclová, Jitka and Vaculová, Jitka and Kunovský, Lumír},
article_location = {Praha},
article_number = {3},
doi = {http://dx.doi.org/10.14735/amgh2020233},
keywords = {herpetic esophagitis; children; acyklovir; endoscopy},
language = {eng},
issn = {1804-7874},
journal = {Gastroenterologie a Hepatologie},
title = {Herpetic esophagitis in a 7-year-old immunocompetent patient},
url = {http://www.csgh.info/en/article/herpetic-esophagitis-in-a-7-year-old-immunocompetent-patient-11141},
volume = {74},
year = {2020}
}
TY - JOUR
ID - 1670809
AU - Jabandžiev, Petr - Jouza, Martin - Pecl, Jakub - Urík, Milan - Papež, Jan - Pinkasová, Tereza - Slabá, Kateřina - Trna, Jan - Kyclová, Jitka - Vaculová, Jitka - Kunovský, Lumír
PY - 2020
TI - Herpetic esophagitis in a 7-year-old immunocompetent patient
JF - Gastroenterologie a Hepatologie
VL - 74
IS - 3
SP - 233-237
EP - 233-237
PB - Ambit Media a.s.
SN - 18047874
KW - herpetic esophagitis
KW - children
KW - acyklovir
KW - endoscopy
UR - http://www.csgh.info/en/article/herpetic-esophagitis-in-a-7-year-old-immunocompetent-patient-11141
L2 - http://www.csgh.info/en/article/herpetic-esophagitis-in-a-7-year-old-immunocompetent-patient-11141
N2 - Herpetic esophagitis is a disease diagnosed especially in immunocompromised patients. Although the disease is rare in immunocompetent individuals, the diagnosis should be considered in the presence of its acute triad of clinical symptoms – odynophagia, chest pain, and fever of unknown origin. Herpes simplex virus type 1 (HSV1) is the most common causative agent. In the majority of cases, the disease develops by re-activation of latent HSV1 infection or, rather rarely, by primo-infection. The basis of diagnosis is endoscopic examination of the esophagus with biopsy and direct detection of the virus in the bioptic sample. In immunocompromised patients, treatment with acyclovir, which is the first-line virostatic in this indication, is always indicated. In immunocompetent patients, this is a self-limiting disease, where in most cases merely symptomatic treatment is sufficient. This case report describes an immunocompetent patient with a suddenly occurring typical triad of symptoms caused by herpetic esophagitis. The diagnosis was confirmed by the presence of viral DNA as determined by polymerase chain reaction from a sample taken during endoscopic examination. Due to the more severe course of the disease, the patient was treated with acyclovir and the general condition and local endoscopic findings then quickly improved.
ER -
JABANDŽIEV, Petr, Martin JOUZA, Jakub PECL, Milan URÍK, Jan PAPEŽ, Tereza PINKASOVÁ, Kateřina SLABÁ, Jan TRNA, Jitka KYCLOVÁ, Jitka VACULOVÁ a Lumír KUNOVSKÝ. Herpetic esophagitis in a 7-year-old immunocompetent patient. \textit{Gastroenterologie a Hepatologie}. Praha: Ambit Media a.s., 2020, roč.~74, č.~3, s.~233-237. ISSN~1804-7874. Dostupné z: https://dx.doi.org/10.14735/amgh2020233.
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