Mathematical modeling of enrichment of estrogens in water
samples using reverse osmosis device

J 2020

Mathematical modeling of enrichment of estrogens in water samples using reverse osmosis device

SIEGEL, Jan, Chimi WANGMO, Jiri CUHORKA, Alena OTOUPALÍKOVÁ, Michal BITTNER et. al.

Basic information

Original name

Mathematical modeling of enrichment of estrogens in water samples using reverse osmosis device

Authors

SIEGEL, Jan (203 Czech Republic), Chimi WANGMO (64 Bhutan, belonging to the institution), Jiri CUHORKA (203 Czech Republic), Alena OTOUPALÍKOVÁ (203 Czech Republic, belonging to the institution) and Michal BITTNER (203 Czech Republic, guarantor, belonging to the institution)

Edition

Environmental Technology and Innovation, Amsterdam, Elsevier, 2020, 2352-1864

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10511 Environmental sciences

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 5.263

RIV identification code

RIV/00216224:14310/20:00114845

Organization unit

Faculty of Science

DOI

http://dx.doi.org/10.1016/j.eti.2019.100584

UT WoS

000525317700035

Keywords in English

Reverse osmosis; Estrogens; Sample enrichment; LC/MS analysis

Abstract

V originále

Estrogens that constitute some of the potent endocrine disruptors are present in the water environment in very low concentrations (below ng/L) requiring sample enrichment to increase its concentration prior to an analytical determination. Currently, solid-phase extraction is the most commonly used enrichment method, but reverse osmosis (RO) may provide a promising alternative with the advantage of maintaining whole water sample including hydrophilic constituents such as humic substances. Subsequent in vitro assessment of such complex samples can provide more realistic information on their estrogenicity. Therefore, a novel experimental enrichment device employing the RO process using a flat-sheet membrane was developed for sample enrichment. In the current study, we aim to develop a mathematical model describing the RO enrichment process using the novel device. The mathematical model was created in MATLAB-Simulink software and validated with experimental results. NaCl at 0.2 and 2 g/L and tap water spiked with 17 alpha-ethynylestradiol (EE2) at concentrations of 10 and 50 ng/L were used as model compounds. A mean relative error between the model and experimental results were 1.5 and 0.9 % for NaCl samples, and 17.3 and 14.4 % for E2, respectively. These results suggest the usefulness of the model for describing the RO system and suitability of the RO device for the enrichment of estrogens prior to instrumental or in vitro analysis.

Links

EF16_013/0001761, research and development project

Name: RECETOX RI

LM2015051, research and development project

Name: Centrum pro výzkum toxických látek v prostředí (Acronym: RECETOX RI)

Investor: Ministry of Education, Youth and Sports of the CR

TG02010067, research and development project

Name: Rozvoj systému komercializace výsledků VaV na Masarykově univerzitě (Acronym: Rozvoj systému komercializace na MU)

Investor: Technology Agency of the Czech Republic, Subprogram 1

Citovat

SIEGEL, Jan, Chimi WANGMO, Jiri CUHORKA, Alena OTOUPALÍKOVÁ and Michal BITTNER. Mathematical modeling of enrichment of estrogens in water samples using reverse osmosis device. Environmental Technology and Innovation. Amsterdam: Elsevier, 2020, vol. 17, February 2020, p. 1-10. ISSN 2352-1864. Available from: https://dx.doi.org/10.1016/j.eti.2019.100584.

@article{1672037,
   author = {Siegel, Jan and Wangmo, Chimi and Cuhorka, Jiri and Otoupalíková, Alena and Bittner, Michal},
   article_location = {Amsterdam},
   article_number = {February 2020},
   doi = {http://dx.doi.org/10.1016/j.eti.2019.100584},
   keywords = {Reverse osmosis; Estrogens; Sample enrichment; LC/MS analysis},
   language = {eng},
   issn = {2352-1864},
   journal = {Environmental Technology and Innovation},
   title = {Mathematical modeling of enrichment of estrogens in water samples using reverse osmosis device},
   url = {https://www.sciencedirect.com/science/article/pii/S2352186419303694?via%3Dihub},
   volume = {17},
   year = {2020}
}

TY  - JOUR
ID  - 1672037
AU  - Siegel, Jan - Wangmo, Chimi - Cuhorka, Jiri - Otoupalíková, Alena - Bittner, Michal
PY  - 2020
TI  - Mathematical modeling of enrichment of estrogens in water samples using reverse osmosis device
JF  - Environmental Technology and Innovation
VL  - 17
IS  - February 2020
SP  - 1-10
EP  - 1-10
PB  - Elsevier
SN  - 23521864
KW  - Reverse osmosis
KW  - Estrogens
KW  - Sample enrichment
KW  - LC/MS analysis
UR  - https://www.sciencedirect.com/science/article/pii/S2352186419303694?via%3Dihub
L2  - https://www.sciencedirect.com/science/article/pii/S2352186419303694?via%3Dihub
N2  - Estrogens that constitute some of the potent endocrine disruptors are present in the water environment in very low concentrations (below ng/L) requiring sample enrichment to increase its concentration prior to an analytical determination. Currently, solid-phase extraction is the most commonly used enrichment method, but reverse osmosis (RO) may provide a promising alternative with the advantage of maintaining whole water sample including hydrophilic constituents such as humic substances. Subsequent in vitro assessment of such complex samples can provide more realistic information on their estrogenicity. Therefore, a novel experimental enrichment device employing the RO process using a flat-sheet membrane was developed for sample enrichment. In the current study, we aim to develop a mathematical model describing the RO enrichment process using the novel device. The mathematical model was created in MATLAB-Simulink software and validated with experimental results. NaCl at 0.2 and 2 g/L and tap water spiked with 17 alpha-ethynylestradiol (EE2) at concentrations of 10 and 50 ng/L were used as model compounds. A mean relative error between the model and experimental results were 1.5 and 0.9 % for NaCl samples, and 17.3 and 14.4 % for E2, respectively. These results suggest the usefulness of the model for describing the RO system and suitability of the RO device for the enrichment of estrogens prior to instrumental or in vitro analysis.
ER  -

SIEGEL, Jan, Chimi WANGMO, Jiri CUHORKA, Alena OTOUPALÍKOVÁ and Michal BITTNER. Mathematical modeling of enrichment of estrogens in water samples using reverse osmosis device. \textit{Environmental Technology and Innovation}. Amsterdam: Elsevier, 2020, vol.~17, February 2020, p.~1-10. ISSN~2352-1864. Available from: https://dx.doi.org/10.1016/j.eti.2019.100584.

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