Ozonization of Tissue Sections for MALDI MS Imaging of
Carbon-Carbon Double Bond Positional Isomers of Phospholipids

J 2020

Ozonization of Tissue Sections for MALDI MS Imaging of Carbon-Carbon Double Bond Positional Isomers of Phospholipids

BEDNAŘÍK, Antonín, Jan PREISLER, Dominika BEZDEKOVÁ, Markéta MACHÁLKOVÁ, Michal HENDRYCH et. al.

Basic information

Original name

Ozonization of Tissue Sections for MALDI MS Imaging of Carbon-Carbon Double Bond Positional Isomers of Phospholipids

Authors

BEDNAŘÍK, Antonín (203 Czech Republic, guarantor, belonging to the institution), Jan PREISLER (203 Czech Republic, belonging to the institution), Dominika BEZDEKOVÁ (703 Slovakia, belonging to the institution), Markéta MACHÁLKOVÁ (203 Czech Republic, belonging to the institution), Michal HENDRYCH (203 Czech Republic, belonging to the institution), Jarmila NAVRÁTILOVÁ (203 Czech Republic, belonging to the institution), Lucia KNOPFOVÁ (203 Czech Republic, belonging to the institution), Eugene MOSKOVETS (643 Russian Federation), Jens SOLTWISH (276 Germany) and Klaus DREISEWERD (276 Germany)

Edition

Analytical Chemistry, Washington, D.C. American Chemical Society, 2020, 0003-2700

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10406 Analytical chemistry

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 6.986

RIV identification code

RIV/00216224:14310/20:00114258

Organization unit

Faculty of Science

DOI

http://dx.doi.org/10.1021/acs.analchem.0c00641

UT WoS

000530658600012

Keywords (in Czech)

ozonolýza; MALDI MS zobrazování; izomery lišící se polohou dvojné vazby; fosfolipidy; střevo

Keywords in English

ozonolysis; MALDI MS imaging; double bond positional isomers; phospholipids; colon

Abstract

V originále

A particular traightforward derivatization technique for an on-tissue ozonization that enables MALDI MS/MS imaging of C=C double bond isomers of unsaturated phospholipids in tissue sections was developed.

Links

GJ19-20927Y, research and development project

Name: MALDI MS zobrazování izomerů lipidů lišících se pozicí dvojné vazby uhlík-uhlík

Investor: Czech Science Foundation

LQ1601, research and development project

Name: CEITEC 2020 (Acronym: CEITEC2020)

Investor: Ministry of Education, Youth and Sports of the CR

MUNI/G/0974/2016, interní kód MU

Name: Optimalizace cílené terapie kolorektálního karcinomu ovlivňováním účinnosti penetrace a cytotoxicity regulátorů buněčných signalizací

Investor: Masaryk University, INTERDISCIPLINARY - Interdisciplinary research projects

Citovat

BEDNAŘÍK, Antonín, Jan PREISLER, Dominika BEZDEKOVÁ, Markéta MACHÁLKOVÁ, Michal HENDRYCH, Jarmila NAVRÁTILOVÁ, Lucia KNOPFOVÁ, Eugene MOSKOVETS, Jens SOLTWISH and Klaus DREISEWERD. Ozonization of Tissue Sections for MALDI MS Imaging of Carbon-Carbon Double Bond Positional Isomers of Phospholipids. Analytical Chemistry. Washington, D.C.: American Chemical Society, 2020, vol. 92, No 9, p. 6245-6250. ISSN 0003-2700. Available from: https://dx.doi.org/10.1021/acs.analchem.0c00641.

@article{1673181,
   author = {Bednařík, Antonín and Preisler, Jan and Bezdeková, Dominika and Machálková, Markéta and Hendrych, Michal and Navrátilová, Jarmila and Knopfová, Lucia and Moskovets, Eugene and Soltwish, Jens and Dreisewerd, Klaus},
   article_location = {Washington, D.C.},
   article_number = {9},
   doi = {http://dx.doi.org/10.1021/acs.analchem.0c00641},
   keywords = {ozonolysis; MALDI MS imaging; double bond positional isomers; phospholipids; colon},
   language = {eng},
   issn = {0003-2700},
   journal = {Analytical Chemistry},
   title = {Ozonization of Tissue Sections for MALDI MS Imaging of Carbon-Carbon Double Bond Positional Isomers of Phospholipids},
   url = {https://pubs.acs.org/doi/abs/10.1021/acs.analchem.0c00641},
   volume = {92},
   year = {2020}
}

TY  - JOUR
ID  - 1673181
AU  - Bednařík, Antonín - Preisler, Jan - Bezdeková, Dominika - Machálková, Markéta - Hendrych, Michal - Navrátilová, Jarmila - Knopfová, Lucia - Moskovets, Eugene - Soltwish, Jens - Dreisewerd, Klaus
PY  - 2020
TI  - Ozonization of Tissue Sections for MALDI MS Imaging of Carbon-Carbon Double Bond Positional Isomers of Phospholipids
JF  - Analytical Chemistry
VL  - 92
IS  - 9
SP  - 6245-6250
EP  - 6245-6250
PB  - American Chemical Society
SN  - 00032700
KW  - ozonolysis
KW  - MALDI MS imaging
KW  - double bond positional isomers
KW  - phospholipids
KW  - colon
UR  - https://pubs.acs.org/doi/abs/10.1021/acs.analchem.0c00641
L2  - https://pubs.acs.org/doi/abs/10.1021/acs.analchem.0c00641
N2  - A particular traightforward derivatization technique for an on-tissue ozonization that enables MALDI MS/MS imaging of C=C double bond isomers of unsaturated phospholipids in tissue sections was developed.
ER  -

BEDNAŘÍK, Antonín, Jan PREISLER, Dominika BEZDEKOVÁ, Markéta MACHÁLKOVÁ, Michal HENDRYCH, Jarmila NAVRÁTILOVÁ, Lucia KNOPFOVÁ, Eugene MOSKOVETS, Jens SOLTWISH and Klaus DREISEWERD. Ozonization of Tissue Sections for MALDI MS Imaging of Carbon-Carbon Double Bond Positional Isomers of Phospholipids. \textit{Analytical Chemistry}. Washington, D.C.: American Chemical Society, 2020, vol.~92, No~9, p.~6245-6250. ISSN~0003-2700. Available from: https://dx.doi.org/10.1021/acs.analchem.0c00641.

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