JARKOVSKÝ, Jiří, Jindřich ŠPINAR, Benoit TYL, Francoise FOUGEROUSSE, Jiří VÍTOVEC, Ales LINHART, Petr WIDIMSKY, Roman MIKLÍK, Lenka ŠPINAROVÁ, Jan BELOHLAVEK, Filip MALEK, Marián FELŠŐCI, Jiri KETTNER, Petr OSTADAL, Jan VACLAVIK, Ladislav DUŠEK, Petr LOKAJ, Alexandre MEBAZAA, Alain Cohen SOLAL and Jiří PAŘENICA. Heart rate as an independent predictor of long term mortality of acute heart failure patients in sinus rhythm according to their ejection fraction: data from the AHEAD registry. European Journal of Internal Medicine. AMSTERDAM: ELSEVIER, 2020, vol. 78, AUG 2020, p. 88-94. ISSN 0953-6205. Available from: https://dx.doi.org/10.1016/j.ejim.2020.04.022.
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Basic information
Original name Heart rate as an independent predictor of long term mortality of acute heart failure patients in sinus rhythm according to their ejection fraction: data from the AHEAD registry
Authors JARKOVSKÝ, Jiří (203 Czech Republic, belonging to the institution), Jindřich ŠPINAR (203 Czech Republic, belonging to the institution), Benoit TYL (250 France), Francoise FOUGEROUSSE (250 France), Jiří VÍTOVEC (203 Czech Republic, belonging to the institution), Ales LINHART (203 Czech Republic), Petr WIDIMSKY (203 Czech Republic), Roman MIKLÍK (203 Czech Republic), Lenka ŠPINAROVÁ (203 Czech Republic, belonging to the institution), Jan BELOHLAVEK (203 Czech Republic), Filip MALEK (203 Czech Republic), Marián FELŠŐCI (703 Slovakia, belonging to the institution), Jiri KETTNER (203 Czech Republic), Petr OSTADAL (203 Czech Republic), Jan VACLAVIK (203 Czech Republic), Ladislav DUŠEK (203 Czech Republic, belonging to the institution), Petr LOKAJ (203 Czech Republic, belonging to the institution), Alexandre MEBAZAA (250 France), Alain Cohen SOLAL (250 France) and Jiří PAŘENICA (203 Czech Republic, belonging to the institution).
Edition European Journal of Internal Medicine, AMSTERDAM, ELSEVIER, 2020, 0953-6205.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30218 General and internal medicine
Country of publisher Netherlands
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 4.487
RIV identification code RIV/00216224:14110/20:00116142
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1016/j.ejim.2020.04.022
UT WoS 000553841300018
Keywords in English Acute heart failure; AHEAD; Prognosis; Sinus rhythm; Heart rate; Preserved ejection fraction
Tags 14110115, 14110211, 14119612, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 6/8/2020 09:37.
Abstract
Background: Heart rate (HR) at admission in patients with acute heart failure (AHF) has been shown to be an important risk marker of in-hospital mortality. However, its relation with mid and long-term prognosis as well as the impact of Ejection Fraction (EF) is unknown. Our objective was to study the relationship between long-term survival and HR at admission depending on EF in a cohort of patients hospitalized for AHF. Methods: We analyzed the data of 2335 patients in sinus rhythm hospitalized for AHF from AHEAD registry. Patients with cardiogenic shock and AHF from surgical or non-cardiac etiology were excluded. Results: Survival rates at 6 and 12 months were 84.8% and 78% respectively. Increased age, decreased diastolic BP, lack of PCI during hospitalization, increased creatinine level and increased HR (with different cut-offs according to EF categories) were found as predictors whatever the EF at 6 and 12 months. Optimal prognostic cut-offs of heart rate were identified for Heart Failure with reduced EF at 100 bpm, for Heart Failure with mid-range EF at 90 bpm and for Heart Failure with preserved EF at 80 bpm for both 6 and 12 months. Conclusion: Our study suggests that HR at admission appears to be an independent prognostic parameter in AHF patients in sinus rhythm irrespective of EF and can be used to classify patients according to the severity of the disease.
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