Assessment of left ventricular volumes and ejection fraction
using ultra-low-dose thallium-201 SPECT on a CZT camera: a
comparison with magnetic resonance imaging

J 2022

Assessment of left ventricular volumes and ejection fraction using ultra-low-dose thallium-201 SPECT on a CZT camera: a comparison with magnetic resonance imaging

SALA, Marek, Vladimír KINCL, Milan KAMÍNEK, Jiří VAŠINA, Jan MÁCHAL et. al.

Basic information

Original name

Assessment of left ventricular volumes and ejection fraction using ultra-low-dose thallium-201 SPECT on a CZT camera: a comparison with magnetic resonance imaging

Authors

SALA, Marek (203 Czech Republic, belonging to the institution), Vladimír KINCL (203 Czech Republic, guarantor, belonging to the institution), Milan KAMÍNEK (203 Czech Republic), Jiří VAŠINA (203 Czech Republic), Jan MÁCHAL (203 Czech Republic, belonging to the institution), Roman PANOVSKÝ (203 Czech Republic, belonging to the institution), Věra FEITOVÁ (203 Czech Republic), Lukáš OPATŘIL (203 Czech Republic, belonging to the institution) and Tomas HOLECEK (203 Czech Republic)

Edition

Journal of Nuclear Cardiology, New York, Springer, 2022, 1071-3581

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30201 Cardiac and Cardiovascular systems

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 2.400

RIV identification code

RIV/00216224:14110/22:00124847

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1007/s12350-020-02161-w

UT WoS

000532890600004

Keywords in English

Left ventricular ejection fraction; Volumes; Myocardial mass; CZT; thallium

Abstract

V originále

Background Cadmium-Zinc-Telluride (CZT) technology allows use of low activities of radiopharmaceuticals. The aim was to verify the values of left ventricular volume parameters, obtained via ultra-low-dose thallium Single Photon Emission Computed Tomography (SPECT) using a CZT camera. Methods and Results Forty-five patients referred for an assessment of myocardial perfusion or viability imaging were examined using CZT-SPECT and 1.5 T magnetic resonance (MRI) scanner. The ultra-low-dose protocol with 0.5 Mbq 201-Tl per kg of body weight was used. The values of end-systolic (ESV) and end-diastolic volumes (EDV), left ventricular ejection fraction (EF) and myocardial mass (MM) were assessed using both techniques. A very good correlation was found between the EF, ESV, and EDV values assessed with CZT-SPECT and cardiac magnetic resonance MRI; the Pearson coefficients were 0.86, 0.95, and 0.91, respectively. A moderate correlation was found for myocardial mass, r = 0.57. Compared to MRI, SPECT systematically overestimated ESV and MM, while it underestimates the EF, with P <= .001 in all cases. There was no difference in EDV estimation. Conclusions Left ventricular volumes and ejection fraction assessed via ultra-low-dose CZT-SPECT showed very good correlation with the values obtained by MRI. A moderate correlation was found for myocardial mass.

Links

MUNI/A/1685/2020, interní kód MU

Name: Nové trendy v diagnostice a terapii kardiomyopatií

Investor: Masaryk University

Citovat

SALA, Marek, Vladimír KINCL, Milan KAMÍNEK, Jiří VAŠINA, Jan MÁCHAL, Roman PANOVSKÝ, Věra FEITOVÁ, Lukáš OPATŘIL and Tomas HOLECEK. Assessment of left ventricular volumes and ejection fraction using ultra-low-dose thallium-201 SPECT on a CZT camera: a comparison with magnetic resonance imaging. Journal of Nuclear Cardiology. New York: Springer, 2022, vol. 29, No 1, p. 181-187. ISSN 1071-3581. Available from: https://dx.doi.org/10.1007/s12350-020-02161-w.

@article{1674061,
   author = {Sala, Marek and Kincl, Vladimír and Kamínek, Milan and Vašina, Jiří and Máchal, Jan and Panovský, Roman and Feitová, Věra and Opatřil, Lukáš and Holecek, Tomas},
   article_location = {New York},
   article_number = {1},
   doi = {http://dx.doi.org/10.1007/s12350-020-02161-w},
   keywords = {Left ventricular ejection fraction; Volumes; Myocardial mass; CZT; thallium},
   language = {eng},
   issn = {1071-3581},
   journal = {Journal of Nuclear Cardiology},
   title = {Assessment of left ventricular volumes and ejection fraction using ultra-low-dose thallium-201 SPECT on a CZT camera: a comparison with magnetic resonance imaging},
   url = {https://link.springer.com/article/10.1007%2Fs12350-020-02161-w},
   volume = {29},
   year = {2022}
}

TY  - JOUR
ID  - 1674061
AU  - Sala, Marek - Kincl, Vladimír - Kamínek, Milan - Vašina, Jiří - Máchal, Jan - Panovský, Roman - Feitová, Věra - Opatřil, Lukáš - Holecek, Tomas
PY  - 2022
TI  - Assessment of left ventricular volumes and ejection fraction using ultra-low-dose thallium-201 SPECT on a CZT camera: a comparison with magnetic resonance imaging
JF  - Journal of Nuclear Cardiology
VL  - 29
IS  - 1
SP  - 181-187
EP  - 181-187
PB  - Springer
SN  - 10713581
KW  - Left ventricular ejection fraction
KW  - Volumes
KW  - Myocardial mass
KW  - CZT
KW  - thallium
UR  - https://link.springer.com/article/10.1007%2Fs12350-020-02161-w
L2  - https://link.springer.com/article/10.1007%2Fs12350-020-02161-w
N2  - Background Cadmium-Zinc-Telluride (CZT) technology allows use of low activities of radiopharmaceuticals. The aim was to verify the values of left ventricular volume parameters, obtained via ultra-low-dose thallium Single Photon Emission Computed Tomography (SPECT) using a CZT camera. Methods and Results Forty-five patients referred for an assessment of myocardial perfusion or viability imaging were examined using CZT-SPECT and 1.5 T magnetic resonance (MRI) scanner. The ultra-low-dose protocol with 0.5 Mbq 201-Tl per kg of body weight was used. The values of end-systolic (ESV) and end-diastolic volumes (EDV), left ventricular ejection fraction (EF) and myocardial mass (MM) were assessed using both techniques. A very good correlation was found between the EF, ESV, and EDV values assessed with CZT-SPECT and cardiac magnetic resonance MRI; the Pearson coefficients were 0.86, 0.95, and 0.91, respectively. A moderate correlation was found for myocardial mass, r = 0.57. Compared to MRI, SPECT systematically overestimated ESV and MM, while it underestimates the EF, with P <= .001 in all cases. There was no difference in EDV estimation. Conclusions Left ventricular volumes and ejection fraction assessed via ultra-low-dose CZT-SPECT showed very good correlation with the values obtained by MRI. A moderate correlation was found for myocardial mass.
ER  -

SALA, Marek, Vladimír KINCL, Milan KAMÍNEK, Jiří VAŠINA, Jan MÁCHAL, Roman PANOVSKÝ, Věra FEITOVÁ, Lukáš OPATŘIL and Tomas HOLECEK. Assessment of left ventricular volumes and ejection fraction using ultra-low-dose thallium-201 SPECT on a CZT camera: a comparison with magnetic resonance imaging. \textit{Journal of Nuclear Cardiology}. New York: Springer, 2022, vol.~29, No~1, p.~181-187. ISSN~1071-3581. Available from: https://dx.doi.org/10.1007/s12350-020-02161-w.

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