Detailed Information on Publication Record
2020
Executable Biochemical Space for Specification and Analysis of Biochemical Systems
TROJÁK, Matej, David ŠAFRÁNEK, Lukrécia MERTOVÁ and Luboš BRIMBasic information
Original name
Executable Biochemical Space for Specification and Analysis of Biochemical Systems
Authors
Edition
7th Workshop on Hybrid Systems and Biology, 2020
Other information
Language
English
Type of outcome
Prezentace na konferencích
Field of Study
10201 Computer sciences, information science, bioinformatics
Country of publisher
Czech Republic
Confidentiality degree
není předmětem státního či obchodního tajemství
Organization unit
Faculty of Informatics
Keywords in English
systems biology; rule-based modelling; annotation
Tags
International impact, Reviewed
Změněno: 15/4/2021 11:40, doc. RNDr. David Šafránek, Ph.D.
Abstract
V originále
We present a rule-based language called Biochemical Space Language (BCSL) as an integral part of a general framework called Comprehensive Modelling Platform, developed for comprehensive modelling in systems biology. The general goal of the platform is to respect the need for maintaining existing ODE models but allows to align them with a mechanistic rule-based description that is understandable by biologists, compact in size, executable in terms of allowing basic analysis tasks ensuring consistency of the description, and provides links to existing bioinformatics annotation databases. Such a comprehensive solution allows to support effort of modellers in building mathematical models that have clear biochemical meaning and can be easily integrated. Moreover, mechanistic descriptions can be later used as computational models having all advantages of rule-based modelling.
Links
| GA15-11089S, research and development project |
| ||
| MUNI/A/1050/2019, interní kód MU |
|