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@article{1678138,
author = {Pupíková, Monika and Rektorová, Irena},
article_location = {Wien},
article_number = {5},
doi = {http://dx.doi.org/10.1007/s00702-019-02113-w},
keywords = {Brain stimulation; Cognitive training; Mild cognitive impairment; Non-pharmacological interventions; Parkinson's disease; Physical therapy},
language = {eng},
issn = {0300-9564},
journal = {Journal of Neural Transmission},
title = {Non-pharmacological management of cognitive impairment in Parkinson’s disease},
url = {https://link.springer.com/article/10.1007/s00702-019-02113-w},
volume = {127},
year = {2020}
}
TY - JOUR
ID - 1678138
AU - Pupíková, Monika - Rektorová, Irena
PY - 2020
TI - Non-pharmacological management of cognitive impairment in Parkinson’s disease
JF - Journal of Neural Transmission
VL - 127
IS - 5
SP - 799-820
EP - 799-820
PB - Springer Wien
SN - 03009564
KW - Brain stimulation
KW - Cognitive training
KW - Mild cognitive impairment
KW - Non-pharmacological interventions
KW - Parkinson's disease
KW - Physical therapy
UR - https://link.springer.com/article/10.1007/s00702-019-02113-w
L2 - https://link.springer.com/article/10.1007/s00702-019-02113-w
N2 - We evaluated the therapeutic effects of non-pharmacological interventions (cognitive training, physical activity, and non-invasive brain stimulation) on cognitive symptoms in Parkinson's disease. A comprehensive literature search for non-pharmacological intervention randomized controlled trials was performed and effect sizes were calculated for each suitable study intervention approach and cognitive domain. Despite the heterogeneity of the study results, we report level B evidence for the probable efficacy of cognitive training in improving or maintaining attention/working memory and memory domains. Level C (possible efficacy) evidence was found for specific physical training types with respect to enhancing executive functions. Non-invasive brain stimulation techniques and combinatorial approaches show preliminary but promising results. Prediction markers evaluating distinct treatment responses should be identified that would help to choose the best candidates for specific treatment strategies and cognitive symptoms. Future directions and recommendations are discussed.
ER -
PUPÍKOVÁ, Monika and Irena REKTOROVÁ. Non-pharmacological management of cognitive impairment in Parkinson’s disease. \textit{Journal of Neural Transmission}. Wien: Springer Wien, 2020, vol.~127, No~5, p.~799-820. ISSN~0300-9564. Available from: https://dx.doi.org/10.1007/s00702-019-02113-w.
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