Non-pharmacological management of cognitive impairment in
Parkinson’s disease

J 2020

Non-pharmacological management of cognitive impairment in Parkinson’s disease

PUPÍKOVÁ, Monika and Irena REKTOROVÁ

Basic information

Original name

Non-pharmacological management of cognitive impairment in Parkinson’s disease

Authors

PUPÍKOVÁ, Monika (203 Czech Republic, belonging to the institution) and Irena REKTOROVÁ (203 Czech Republic, guarantor, belonging to the institution)

Edition

Journal of Neural Transmission, Wien, Springer Wien, 2020, 0300-9564

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30103 Neurosciences

Country of publisher

Austria

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 3.575

RIV identification code

RIV/00216224:14740/20:00116387

Organization unit

Central European Institute of Technology

DOI

http://dx.doi.org/10.1007/s00702-019-02113-w

UT WoS

000534796600013

Keywords in English

Brain stimulation; Cognitive training; Mild cognitive impairment; Non-pharmacological interventions; Parkinson's disease; Physical therapy

Abstract

V originále

We evaluated the therapeutic effects of non-pharmacological interventions (cognitive training, physical activity, and non-invasive brain stimulation) on cognitive symptoms in Parkinson's disease. A comprehensive literature search for non-pharmacological intervention randomized controlled trials was performed and effect sizes were calculated for each suitable study intervention approach and cognitive domain. Despite the heterogeneity of the study results, we report level B evidence for the probable efficacy of cognitive training in improving or maintaining attention/working memory and memory domains. Level C (possible efficacy) evidence was found for specific physical training types with respect to enhancing executive functions. Non-invasive brain stimulation techniques and combinatorial approaches show preliminary but promising results. Prediction markers evaluating distinct treatment responses should be identified that would help to choose the best candidates for specific treatment strategies and cognitive symptoms. Future directions and recommendations are discussed.

Links

LQ1601, research and development project

Name: CEITEC 2020 (Acronym: CEITEC2020)

Investor: Ministry of Education, Youth and Sports of the CR

NV18-04-00256, research and development project

Name: Efekt transkraniální stimulace tDCS na zrakovou pozornost u pacientů s mírnou kognitivní poruchou - studie kombinující MRI a neinvazivní mozkovou stimulaci

Investor: Ministry of Health of the CR

Citovat

PUPÍKOVÁ, Monika and Irena REKTOROVÁ. Non-pharmacological management of cognitive impairment in Parkinson’s disease. Journal of Neural Transmission. Wien: Springer Wien, 2020, vol. 127, No 5, p. 799-820. ISSN 0300-9564. Available from: https://dx.doi.org/10.1007/s00702-019-02113-w.

@article{1678138,
   author = {Pupíková, Monika and Rektorová, Irena},
   article_location = {Wien},
   article_number = {5},
   doi = {http://dx.doi.org/10.1007/s00702-019-02113-w},
   keywords = {Brain stimulation; Cognitive training; Mild cognitive impairment; Non-pharmacological interventions; Parkinson's disease; Physical therapy},
   language = {eng},
   issn = {0300-9564},
   journal = {Journal of Neural Transmission},
   title = {Non-pharmacological management of cognitive impairment in Parkinson’s disease},
   url = {https://link.springer.com/article/10.1007/s00702-019-02113-w},
   volume = {127},
   year = {2020}
}

TY  - JOUR
ID  - 1678138
AU  - Pupíková, Monika - Rektorová, Irena
PY  - 2020
TI  - Non-pharmacological management of cognitive impairment in Parkinson’s disease
JF  - Journal of Neural Transmission
VL  - 127
IS  - 5
SP  - 799-820
EP  - 799-820
PB  - Springer Wien
SN  - 03009564
KW  - Brain stimulation
KW  - Cognitive training
KW  - Mild cognitive impairment
KW  - Non-pharmacological interventions
KW  - Parkinson's disease
KW  - Physical therapy
UR  - https://link.springer.com/article/10.1007/s00702-019-02113-w
L2  - https://link.springer.com/article/10.1007/s00702-019-02113-w
N2  - We evaluated the therapeutic effects of non-pharmacological interventions (cognitive training, physical activity, and non-invasive brain stimulation) on cognitive symptoms in Parkinson's disease. A comprehensive literature search for non-pharmacological intervention randomized controlled trials was performed and effect sizes were calculated for each suitable study intervention approach and cognitive domain. Despite the heterogeneity of the study results, we report level B evidence for the probable efficacy of cognitive training in improving or maintaining attention/working memory and memory domains. Level C (possible efficacy) evidence was found for specific physical training types with respect to enhancing executive functions. Non-invasive brain stimulation techniques and combinatorial approaches show preliminary but promising results. Prediction markers evaluating distinct treatment responses should be identified that would help to choose the best candidates for specific treatment strategies and cognitive symptoms. Future directions and recommendations are discussed.
ER  -

PUPÍKOVÁ, Monika and Irena REKTOROVÁ. Non-pharmacological management of cognitive impairment in Parkinson’s disease. \textit{Journal of Neural Transmission}. Wien: Springer Wien, 2020, vol.~127, No~5, p.~799-820. ISSN~0300-9564. Available from: https://dx.doi.org/10.1007/s00702-019-02113-w.

Detailed Information on Publication Record