Aim: The aim of this study was to analyze published studies focusing on quality of life (QoL) in patients with non-healing wounds, with particular focus on assessment tools. Design: Type of study – literature review. Methods: Articles focusing on QoL in patients with non-healing wounds were searched for in various electronic databases using relevant terms. The search was limited to articles in English issued between January 2014 and April 2019, in the electronic databases Scopus, PubMed, and CINAHL. Results: In total, 24 studies were found which met the established criteria. Conclusion: Non-healing wounds significantly affect patients' QoL. Research is leading towards the creation of a standardized QoL tool in patients with chronic wounds, which could be included in the wound care standard care protocol. There are many generic and specific tools for evaluating QoL in patients with non-healing wounds, differing in length and complexity. The Wound-QoL was created by comparing and simplifying proven tools, and the follow-up research has proven it to be internally consistent, valid and reliable, and, due to its ease of use, suitable for re-measuring QoL.