Myocarditis in Relation to Angiographic Findings in Patients
With Provisional Diagnoses of MINOCA

J 2020

Myocarditis in Relation to Angiographic Findings in Patients With Provisional Diagnoses of MINOCA

HAUSVATER, A., N. R. SMILOWITZ, B. Y. Z. LI, G. REDEL-TRAUB, M. QUIEN et. al.

Basic information

Original name

Myocarditis in Relation to Angiographic Findings in Patients With Provisional Diagnoses of MINOCA

Authors

HAUSVATER, A. (840 United States of America), N. R. SMILOWITZ (840 United States of America), B. Y. Z. LI (840 United States of America), G. REDEL-TRAUB (840 United States of America), M. QUIEN (840 United States of America), Y. Z. QIAN (840 United States of America), J. ZHONG (840 United States of America), J. M. NICHOLSON (840 United States of America), G. CAMASTRA (380 Italy), L. BIERE (250 France), Roman PANOVSKÝ (203 Czech Republic, belonging to the institution), M. SA (620 Portugal), E. GERBAUD (250 France), J. B. SELVANAYAGAM (36 Australia), M. H. AL-MALLAH (840 United States of America), T. EMRICH (276 Germany) and H. R. REYNOLDS (840 United States of America, guarantor)

Edition

JACC-CARDIOVASCULAR IMAGING, NEW YORK, ELSEVIER SCIENCE INC, 2020, 1936-878X

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30201 Cardiac and Cardiovascular systems

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 14.805

RIV identification code

RIV/00216224:14110/20:00116548

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1016/j.jcmg.2020.02.037

UT WoS

000569134000009

Keywords in English

cardiac magnetic resonance; myocardial infarction; myocarditis

Abstract

V originále

OBJECTIVES The aim of this study was to determine the prevalence of myocarditis among patients presenting with myocardial infarction with nonobstructive coronary arteries (MINOCA) in relation to the angiographic severity of non-obstructive coronary artery disease (CAD). BACKGROUND MINOCA represents about 6% of all cases of acute myocardial infarction. Myocarditis is a diagnosis that may be identified by cardiac magnetic resonance (CMR) imaging in patients with a provisional diagnosis of MINOCA. METHODS A systematic review was performed to identify studies reporting the results of CMR findings in MINOCA patients with nonobstructive CAD or normal coronary arteries. Study-level and individual patient data meta-analyses were performed using fixed- and random-effects methods. RESULTS Twenty-seven papers were included, with 2,921 patients with MINOCA; CMR findings were reported in 2,866 (98.1%). Myocarditis prevalence was 34.5% (95% confidence interval [CI]: 27.2% to 42.2%) overall and was numerically higher in studies that defined MINOCA as myocardial infarction with angiographicalty normal coronary arteries compared with a definition that permitted nonobstructive CAD (45.9% vs. 32.3%; p = 0.16). In a meta-analysis of individual patient data from 9 of the 27 studies, the pooled prevalence of CMR-confirmed myocarditis was greater in patients with angiographically normal coronary arteries than in those with nonobstructive CAD (51% [95% CI: 47% to 56%] vs. 23% [95% CI: 18% to 27%]; p < 0.001). Men and younger patients with MINOCA were more likely to have myocarditis. Angiographicatly normal coronary arteries were associated with increased odds of myocarditis after adjustment for age and sex (adjusted odds ratio: 2.30; 95% CI: 1.12 to 4.71; p = 0.023). CONCLUSIONS Patients with a provisional diagnosis of MINOCA are more likely to have CMR findings consistent with myocarditis if they have angiographically normal coronary arteries. (C) 2020 by the American College of Cardiology Foundation.

Citovat

HAUSVATER, A., N. R. SMILOWITZ, B. Y. Z. LI, G. REDEL-TRAUB, M. QUIEN, Y. Z. QIAN, J. ZHONG, J. M. NICHOLSON, G. CAMASTRA, L. BIERE, Roman PANOVSKÝ, M. SA, E. GERBAUD, J. B. SELVANAYAGAM, M. H. AL-MALLAH, T. EMRICH and H. R. REYNOLDS. Myocarditis in Relation to Angiographic Findings in Patients With Provisional Diagnoses of MINOCA. JACC-CARDIOVASCULAR IMAGING. NEW YORK: ELSEVIER SCIENCE INC, 2020, vol. 13, No 9, p. 1906-1913. ISSN 1936-878X. Available from: https://dx.doi.org/10.1016/j.jcmg.2020.02.037.

@article{1682081,
   author = {Hausvater, A. and Smilowitz, N. R. and Li, B. Y. Z. and RedelandTraub, G. and Quien, M. and Qian, Y. Z. and Zhong, J. and Nicholson, J. M. and Camastra, G. and Biere, L. and Panovský, Roman and Sa, M. and Gerbaud, E. and Selvanayagam, J. B. and AlandMallah, M. H. and Emrich, T. and Reynolds, H. R.},
   article_location = {NEW YORK},
   article_number = {9},
   doi = {http://dx.doi.org/10.1016/j.jcmg.2020.02.037},
   keywords = {cardiac magnetic resonance; myocardial infarction; myocarditis},
   language = {eng},
   issn = {1936-878X},
   journal = {JACC-CARDIOVASCULAR IMAGING},
   title = {Myocarditis in Relation to Angiographic Findings in Patients With Provisional Diagnoses of MINOCA},
   url = {https://www.sciencedirect.com/science/article/pii/S1936878X20303405?via%3Dihub},
   volume = {13},
   year = {2020}
}

TY  - JOUR
ID  - 1682081
AU  - Hausvater, A. - Smilowitz, N. R. - Li, B. Y. Z. - Redel-Traub, G. - Quien, M. - Qian, Y. Z. - Zhong, J. - Nicholson, J. M. - Camastra, G. - Biere, L. - Panovský, Roman - Sa, M. - Gerbaud, E. - Selvanayagam, J. B. - Al-Mallah, M. H. - Emrich, T. - Reynolds, H. R.
PY  - 2020
TI  - Myocarditis in Relation to Angiographic Findings in Patients With Provisional Diagnoses of MINOCA
JF  - JACC-CARDIOVASCULAR IMAGING
VL  - 13
IS  - 9
SP  - 1906-1913
EP  - 1906-1913
PB  - ELSEVIER SCIENCE INC
SN  - 1936878X
KW  - cardiac magnetic resonance
KW  - myocardial infarction
KW  - myocarditis
UR  - https://www.sciencedirect.com/science/article/pii/S1936878X20303405?via%3Dihub
L2  - https://www.sciencedirect.com/science/article/pii/S1936878X20303405?via%3Dihub
N2  - OBJECTIVES The aim of this study was to determine the prevalence of myocarditis among patients presenting with myocardial infarction with nonobstructive coronary arteries (MINOCA) in relation to the angiographic severity of non-obstructive coronary artery disease (CAD). BACKGROUND MINOCA represents about 6% of all cases of acute myocardial infarction. Myocarditis is a diagnosis that may be identified by cardiac magnetic resonance (CMR) imaging in patients with a provisional diagnosis of MINOCA. METHODS A systematic review was performed to identify studies reporting the results of CMR findings in MINOCA patients with nonobstructive CAD or normal coronary arteries. Study-level and individual patient data meta-analyses were performed using fixed- and random-effects methods. RESULTS Twenty-seven papers were included, with 2,921 patients with MINOCA; CMR findings were reported in 2,866 (98.1%). Myocarditis prevalence was 34.5% (95% confidence interval [CI]: 27.2% to 42.2%) overall and was numerically higher in studies that defined MINOCA as myocardial infarction with angiographicalty normal coronary arteries compared with a definition that permitted nonobstructive CAD (45.9% vs. 32.3%; p = 0.16). In a meta-analysis of individual patient data from 9 of the 27 studies, the pooled prevalence of CMR-confirmed myocarditis was greater in patients with angiographically normal coronary arteries than in those with nonobstructive CAD (51% [95% CI: 47% to 56%] vs. 23% [95% CI: 18% to 27%]; p < 0.001). Men and younger patients with MINOCA were more likely to have myocarditis. Angiographicatly normal coronary arteries were associated with increased odds of myocarditis after adjustment for age and sex (adjusted odds ratio: 2.30; 95% CI: 1.12 to 4.71; p = 0.023). CONCLUSIONS Patients with a provisional diagnosis of MINOCA are more likely to have CMR findings consistent with myocarditis if they have angiographically normal coronary arteries. (C) 2020 by the American College of Cardiology Foundation.
ER  -

HAUSVATER, A., N. R. SMILOWITZ, B. Y. Z. LI, G. REDEL-TRAUB, M. QUIEN, Y. Z. QIAN, J. ZHONG, J. M. NICHOLSON, G. CAMASTRA, L. BIERE, Roman PANOVSKÝ, M. SA, E. GERBAUD, J. B. SELVANAYAGAM, M. H. AL-MALLAH, T. EMRICH and H. R. REYNOLDS. Myocarditis in Relation to Angiographic Findings in Patients With Provisional Diagnoses of MINOCA. \textit{JACC-CARDIOVASCULAR IMAGING}. NEW YORK: ELSEVIER SCIENCE INC, 2020, vol.~13, No~9, p.~1906-1913. ISSN~1936-878X. Available from: https://dx.doi.org/10.1016/j.jcmg.2020.02.037.

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