HAUSVATER, A., N. R. SMILOWITZ, B. Y. Z. LI, G. REDEL-TRAUB, M. QUIEN, Y. Z. QIAN, J. ZHONG, J. M. NICHOLSON, G. CAMASTRA, L. BIERE, Roman PANOVSKÝ, M. SA, E. GERBAUD, J. B. SELVANAYAGAM, M. H. AL-MALLAH, T. EMRICH and H. R. REYNOLDS. Myocarditis in Relation to Angiographic Findings in Patients With Provisional Diagnoses of MINOCA. JACC-CARDIOVASCULAR IMAGING. NEW YORK: ELSEVIER SCIENCE INC, 2020, vol. 13, No 9, p. 1906-1913. ISSN 1936-878X. Available from: https://dx.doi.org/10.1016/j.jcmg.2020.02.037.
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Basic information
Original name Myocarditis in Relation to Angiographic Findings in Patients With Provisional Diagnoses of MINOCA
Authors HAUSVATER, A. (840 United States of America), N. R. SMILOWITZ (840 United States of America), B. Y. Z. LI (840 United States of America), G. REDEL-TRAUB (840 United States of America), M. QUIEN (840 United States of America), Y. Z. QIAN (840 United States of America), J. ZHONG (840 United States of America), J. M. NICHOLSON (840 United States of America), G. CAMASTRA (380 Italy), L. BIERE (250 France), Roman PANOVSKÝ (203 Czech Republic, belonging to the institution), M. SA (620 Portugal), E. GERBAUD (250 France), J. B. SELVANAYAGAM (36 Australia), M. H. AL-MALLAH (840 United States of America), T. EMRICH (276 Germany) and H. R. REYNOLDS (840 United States of America, guarantor).
Edition JACC-CARDIOVASCULAR IMAGING, NEW YORK, ELSEVIER SCIENCE INC, 2020, 1936-878X.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30201 Cardiac and Cardiovascular systems
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 14.805
RIV identification code RIV/00216224:14110/20:00116548
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1016/j.jcmg.2020.02.037
UT WoS 000569134000009
Keywords in English cardiac magnetic resonance; myocardial infarction; myocarditis
Tags 14110115, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 1/10/2020 14:21.
Abstract
OBJECTIVES The aim of this study was to determine the prevalence of myocarditis among patients presenting with myocardial infarction with nonobstructive coronary arteries (MINOCA) in relation to the angiographic severity of non-obstructive coronary artery disease (CAD). BACKGROUND MINOCA represents about 6% of all cases of acute myocardial infarction. Myocarditis is a diagnosis that may be identified by cardiac magnetic resonance (CMR) imaging in patients with a provisional diagnosis of MINOCA. METHODS A systematic review was performed to identify studies reporting the results of CMR findings in MINOCA patients with nonobstructive CAD or normal coronary arteries. Study-level and individual patient data meta-analyses were performed using fixed- and random-effects methods. RESULTS Twenty-seven papers were included, with 2,921 patients with MINOCA; CMR findings were reported in 2,866 (98.1%). Myocarditis prevalence was 34.5% (95% confidence interval [CI]: 27.2% to 42.2%) overall and was numerically higher in studies that defined MINOCA as myocardial infarction with angiographicalty normal coronary arteries compared with a definition that permitted nonobstructive CAD (45.9% vs. 32.3%; p = 0.16). In a meta-analysis of individual patient data from 9 of the 27 studies, the pooled prevalence of CMR-confirmed myocarditis was greater in patients with angiographically normal coronary arteries than in those with nonobstructive CAD (51% [95% CI: 47% to 56%] vs. 23% [95% CI: 18% to 27%]; p < 0.001). Men and younger patients with MINOCA were more likely to have myocarditis. Angiographicatly normal coronary arteries were associated with increased odds of myocarditis after adjustment for age and sex (adjusted odds ratio: 2.30; 95% CI: 1.12 to 4.71; p = 0.023). CONCLUSIONS Patients with a provisional diagnosis of MINOCA are more likely to have CMR findings consistent with myocarditis if they have angiographically normal coronary arteries. (C) 2020 by the American College of Cardiology Foundation.
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