| NODA, Angel A., Islay RODRIGUEZ and David ŠMAJS. Genotyping of Treponema pallidumin Cuba (2018-2019): Increased Circulation of Recombinant Genotype and No New Treponema pallidum Subspeciesendemicum Infection Among Syphilis Patients. Sexually transmitted diseases. Philadelphia: Lippincott Williams & Wilkins, 2020, vol. 47, No 10, p. "E39"-"E41", 3 pp. ISSN 0148-5717. Available from: https://dx.doi.org/10.1097/OLQ.0000000000001217. |
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@article{1685076,
author = {Noda, Angel A. and Rodriguez, Islay and Šmajs, David},
article_location = {Philadelphia},
article_number = {10},
doi = {http://dx.doi.org/10.1097/OLQ.0000000000001217},
keywords = {Treponema pallidumin; Cuba; Syphilis Patients},
language = {eng},
issn = {0148-5717},
journal = {Sexually transmitted diseases},
title = {Genotyping of Treponema pallidumin Cuba (2018-2019): Increased Circulation of Recombinant Genotype and No New Treponema pallidum Subspeciesendemicum Infection Among Syphilis Patients},
url = {https://journals.lww.com/stdjournal/Fulltext/2020/10000/Genotyping_of_Treponema_pallidum_in_Cuba.12.aspx},
volume = {47},
year = {2020}
}
TY - JOUR
ID - 1685076
AU - Noda, Angel A. - Rodriguez, Islay - Šmajs, David
PY - 2020
TI - Genotyping of Treponema pallidumin Cuba (2018-2019): Increased Circulation of Recombinant Genotype and No New Treponema pallidum Subspeciesendemicum Infection Among Syphilis Patients
JF - Sexually transmitted diseases
VL - 47
IS - 10
SP - "E39"-"E41"
EP - "E39"-"E41"
PB - Lippincott Williams & Wilkins
SN - 01485717
KW - Treponema pallidumin
KW - Cuba
KW - Syphilis Patients
UR - https://journals.lww.com/stdjournal/Fulltext/2020/10000/Genotyping_of_Treponema_pallidum_in_Cuba.12.aspx
L2 - https://journals.lww.com/stdjournal/Fulltext/2020/10000/Genotyping_of_Treponema_pallidum_in_Cuba.12.aspx
N2 - Objectives This study aimed to determine the allelic profiles ofTreponema pallidumin patients confirmed with syphilis in Cuba (2018-2019) and to explore mutations leading to macrolide and tetracycline resistance. Methods Multilocus sequence typing and polymerase chain reaction ofrrnloci (23S and 16S rDNA), followed by Sanger sequencing, were used to define the allelic profile of TPA and resistance mutations, respectively. Results Allelic profile 1.3.1 and the recombinant profile were identified, with 15.7.3 having an increased frequency. We did not detect the presence of theT. pallidumsubspeciesendemicumamong syphilis patients, as in previous reports. A high frequency of macrolide-resistant strains and the absence of mutations potentially causing tetracycline resistance were found. Conclusions Understanding the current status of treponemal infection in Cuban patients provides insights into the syphilis epidemiology.
ER -
NODA, Angel A., Islay RODRIGUEZ and David ŠMAJS. Genotyping of Treponema pallidumin Cuba (2018-2019): Increased Circulation of Recombinant Genotype and No New Treponema pallidum Subspeciesendemicum Infection Among Syphilis Patients. \textit{Sexually transmitted diseases}. Philadelphia: Lippincott Williams \&{} Wilkins, 2020, vol.~47, No~10, p.~''E39''-''E41'', 3 pp. ISSN~0148-5717. Available from: https://dx.doi.org/10.1097/OLQ.0000000000001217.
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