NODA, Angel A., Islay RODRIGUEZ and David ŠMAJS. Genotyping of Treponema pallidumin Cuba (2018-2019): Increased Circulation of Recombinant Genotype and No New Treponema pallidum Subspeciesendemicum Infection Among Syphilis Patients. Sexually transmitted diseases. Philadelphia: Lippincott Williams & Wilkins, 2020, vol. 47, No 10, p. "E39"-"E41", 3 pp. ISSN 0148-5717. Available from: https://dx.doi.org/10.1097/OLQ.0000000000001217. |
Other formats:
BibTeX
LaTeX
RIS
@article{1685076, author = {Noda, Angel A. and Rodriguez, Islay and Šmajs, David}, article_location = {Philadelphia}, article_number = {10}, doi = {http://dx.doi.org/10.1097/OLQ.0000000000001217}, keywords = {Treponema pallidumin; Cuba; Syphilis Patients}, language = {eng}, issn = {0148-5717}, journal = {Sexually transmitted diseases}, title = {Genotyping of Treponema pallidumin Cuba (2018-2019): Increased Circulation of Recombinant Genotype and No New Treponema pallidum Subspeciesendemicum Infection Among Syphilis Patients}, url = {https://journals.lww.com/stdjournal/Fulltext/2020/10000/Genotyping_of_Treponema_pallidum_in_Cuba.12.aspx}, volume = {47}, year = {2020} }
TY - JOUR ID - 1685076 AU - Noda, Angel A. - Rodriguez, Islay - Šmajs, David PY - 2020 TI - Genotyping of Treponema pallidumin Cuba (2018-2019): Increased Circulation of Recombinant Genotype and No New Treponema pallidum Subspeciesendemicum Infection Among Syphilis Patients JF - Sexually transmitted diseases VL - 47 IS - 10 SP - "E39"-"E41" EP - "E39"-"E41" PB - Lippincott Williams & Wilkins SN - 01485717 KW - Treponema pallidumin KW - Cuba KW - Syphilis Patients UR - https://journals.lww.com/stdjournal/Fulltext/2020/10000/Genotyping_of_Treponema_pallidum_in_Cuba.12.aspx L2 - https://journals.lww.com/stdjournal/Fulltext/2020/10000/Genotyping_of_Treponema_pallidum_in_Cuba.12.aspx N2 - Objectives This study aimed to determine the allelic profiles ofTreponema pallidumin patients confirmed with syphilis in Cuba (2018-2019) and to explore mutations leading to macrolide and tetracycline resistance. Methods Multilocus sequence typing and polymerase chain reaction ofrrnloci (23S and 16S rDNA), followed by Sanger sequencing, were used to define the allelic profile of TPA and resistance mutations, respectively. Results Allelic profile 1.3.1 and the recombinant profile were identified, with 15.7.3 having an increased frequency. We did not detect the presence of theT. pallidumsubspeciesendemicumamong syphilis patients, as in previous reports. A high frequency of macrolide-resistant strains and the absence of mutations potentially causing tetracycline resistance were found. Conclusions Understanding the current status of treponemal infection in Cuban patients provides insights into the syphilis epidemiology. ER -
NODA, Angel A., Islay RODRIGUEZ and David ŠMAJS. Genotyping of Treponema pallidumin Cuba (2018-2019): Increased Circulation of Recombinant Genotype and No New Treponema pallidum Subspeciesendemicum Infection Among Syphilis Patients. \textit{Sexually transmitted diseases}. Philadelphia: Lippincott Williams \&{} Wilkins, 2020, vol.~47, No~10, p.~''E39''-''E41'', 3 pp. ISSN~0148-5717. Available from: https://dx.doi.org/10.1097/OLQ.0000000000001217.
|