| KUNOVSKÝ, Lumír, Jan LOCHMAN, Zdeněk KALA, Jiří DOLINA, Radek KROUPA, Vladimír PROCHÁZKA, Tomáš GROLICH, Jitka VACULOVÁ, Petr LITZMAN, Tereza DEISSOVÁ, Markéta HANSLIANOVÁ, Petr JABANDŽIEV, Ondřej SLABÝ, Lydie IZAKOVIČOVÁ HOLLÁ and Petra BOŘILOVÁ LINHARTOVÁ. The microbiome of the esophagus, stomach and duodenum in patients with gastroesophageal reflux disease - pilot study. In UEG Week 2020. 2020. ISSN 2050-6414. |
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@proceedings{1685422,
author = {Kunovský, Lumír and Lochman, Jan and Kala, Zdeněk and Dolina, Jiří and Kroupa, Radek and Procházka, Vladimír and Grolich, Tomáš and Vaculová, Jitka and Litzman, Petr and Deissová, Tereza and Hanslianová, Markéta and Jabandžiev, Petr and Slabý, Ondřej and Izakovičová Hollá, Lydie and Bořilová Linhartová, Petra},
booktitle = {UEG Week 2020},
keywords = {microbiome; gastroesophageal reflux disease},
language = {eng},
title = {The microbiome of the esophagus, stomach and duodenum in patients with gastroesophageal reflux disease - pilot study},
year = {2020}
}
TY - CONF
ID - 1685422
AU - Kunovský, Lumír - Lochman, Jan - Kala, Zdeněk - Dolina, Jiří - Kroupa, Radek - Procházka, Vladimír - Grolich, Tomáš - Vaculová, Jitka - Litzman, Petr - Deissová, Tereza - Hanslianová, Markéta - Jabandžiev, Petr - Slabý, Ondřej - Izakovičová Hollá, Lydie - Bořilová Linhartová, Petra
PY - 2020
TI - The microbiome of the esophagus, stomach and duodenum in patients with gastroesophageal reflux disease - pilot study
KW - microbiome
KW - gastroesophageal reflux disease
N2 - Introduction: These days gastroesophageal reflux disease (GERD) represents one of the significant health problems of western countries as a result of several lifestyle factors. Prolonged GERD leads to esophageal inflammation and significantly increases the risk of Barrett’s esophagus (BE) and the subsequent development of esophageal adenocarcinoma (EAC). There is an association between the esophageal microbiome and several esophageal diseases. However, it remains unclear whether the change in microflora leads to esophageal disease, or if this is a side effect of the highly acidic environment created by GERD. Our pilot study aimed to describe oral bacterial biota in patients with GERD and healthy controls from different parts of the esophagus, stomach and duodenum. Detailed microbiome analysis could contribute to early diagnosis and to the application of effective treatment in patients with GERD.
ER -
KUNOVSKÝ, Lumír, Jan LOCHMAN, Zdeněk KALA, Jiří DOLINA, Radek KROUPA, Vladimír PROCHÁZKA, Tomáš GROLICH, Jitka VACULOVÁ, Petr LITZMAN, Tereza DEISSOVÁ, Markéta HANSLIANOVÁ, Petr JABANDŽIEV, Ondřej SLABÝ, Lydie IZAKOVIČOVÁ HOLLÁ and Petra BOŘILOVÁ LINHARTOVÁ. The microbiome of the esophagus, stomach and duodenum in patients with gastroesophageal reflux disease - pilot study. In \textit{UEG Week 2020}. 2020. ISSN~2050-6414.
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