The microbiome of the esophagus, stomach and duodenum in
patients with gastroesophageal reflux disease - pilot study

a 2020

The microbiome of the esophagus, stomach and duodenum in patients with gastroesophageal reflux disease - pilot study

KUNOVSKÝ, Lumír, Jan LOCHMAN, Zdeněk KALA, Jiří DOLINA, Radek KROUPA et. al.

Basic information

Original name

The microbiome of the esophagus, stomach and duodenum in patients with gastroesophageal reflux disease - pilot study

Authors

KUNOVSKÝ, Lumír (203 Czech Republic, guarantor, belonging to the institution), Jan LOCHMAN (203 Czech Republic, belonging to the institution), Zdeněk KALA (203 Czech Republic, belonging to the institution), Jiří DOLINA (203 Czech Republic, belonging to the institution), Radek KROUPA (203 Czech Republic, belonging to the institution), Vladimír PROCHÁZKA (203 Czech Republic, belonging to the institution), Tomáš GROLICH (203 Czech Republic, belonging to the institution), Jitka VACULOVÁ (203 Czech Republic, belonging to the institution), Petr LITZMAN (203 Czech Republic, belonging to the institution), Tereza DEISSOVÁ (203 Czech Republic, belonging to the institution), Markéta HANSLIANOVÁ (203 Czech Republic, belonging to the institution), Petr JABANDŽIEV (203 Czech Republic, belonging to the institution), Ondřej SLABÝ (203 Czech Republic, belonging to the institution), Lydie IZAKOVIČOVÁ HOLLÁ (203 Czech Republic, belonging to the institution) and Petra BOŘILOVÁ LINHARTOVÁ (203 Czech Republic, belonging to the institution)

Edition

UEG Week 2020, 2020

Other information

Language

English

Type of outcome

Konferenční abstrakt

Field of Study

30219 Gastroenterology and hepatology

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 4.623

RIV identification code

RIV/00216224:14110/20:00120076

Organization unit

Faculty of Medicine

ISSN

Keywords in English

microbiome; gastroesophageal reflux disease

Abstract

V originále

Introduction: These days gastroesophageal reflux disease (GERD) represents one of the significant health problems of western countries as a result of several lifestyle factors. Prolonged GERD leads to esophageal inflammation and significantly increases the risk of Barrett’s esophagus (BE) and the subsequent development of esophageal adenocarcinoma (EAC). There is an association between the esophageal microbiome and several esophageal diseases. However, it remains unclear whether the change in microflora leads to esophageal disease, or if this is a side effect of the highly acidic environment created by GERD. Our pilot study aimed to describe oral bacterial biota in patients with GERD and healthy controls from different parts of the esophagus, stomach and duodenum. Detailed microbiome analysis could contribute to early diagnosis and to the application of effective treatment in patients with GERD.

Links

NU20-03-00126, research and development project

Name: Hostitelský mikrobiom ve vztahu k rozvoji Barrettova jícnu a adenokarcinomu jícnu

Investor: Ministry of Health of the CR, Host microbiome in relation to Barrett ́s esophagus and esophageal adenocarcinoma development, Subprogram 1 - standard

Citovat

KUNOVSKÝ, Lumír, Jan LOCHMAN, Zdeněk KALA, Jiří DOLINA, Radek KROUPA, Vladimír PROCHÁZKA, Tomáš GROLICH, Jitka VACULOVÁ, Petr LITZMAN, Tereza DEISSOVÁ, Markéta HANSLIANOVÁ, Petr JABANDŽIEV, Ondřej SLABÝ, Lydie IZAKOVIČOVÁ HOLLÁ and Petra BOŘILOVÁ LINHARTOVÁ. The microbiome of the esophagus, stomach and duodenum in patients with gastroesophageal reflux disease - pilot study. In UEG Week 2020. 2020. ISSN 2050-6414.

@proceedings{1685422,
   author = {Kunovský, Lumír and Lochman, Jan and Kala, Zdeněk and Dolina, Jiří and Kroupa, Radek and Procházka, Vladimír and Grolich, Tomáš and Vaculová, Jitka and Litzman, Petr and Deissová, Tereza and Hanslianová, Markéta and Jabandžiev, Petr and Slabý, Ondřej and Izakovičová Hollá, Lydie and Bořilová Linhartová, Petra},
   booktitle = {UEG Week 2020},
   keywords = {microbiome; gastroesophageal reflux disease},
   language = {eng},
   title = {The microbiome of the esophagus, stomach and duodenum in patients with gastroesophageal reflux disease - pilot study},
   year = {2020}
}

TY  - CONF
ID  - 1685422
AU  - Kunovský, Lumír - Lochman, Jan - Kala, Zdeněk - Dolina, Jiří - Kroupa, Radek - Procházka, Vladimír - Grolich, Tomáš - Vaculová, Jitka - Litzman, Petr - Deissová, Tereza - Hanslianová, Markéta - Jabandžiev, Petr - Slabý, Ondřej - Izakovičová Hollá, Lydie - Bořilová Linhartová, Petra
PY  - 2020
TI  - The microbiome of the esophagus, stomach and duodenum in patients with gastroesophageal reflux disease - pilot study
KW  - microbiome
KW  - gastroesophageal reflux disease
N2  - Introduction: These days gastroesophageal reflux disease (GERD) represents one of the significant health problems of western countries as a result of several lifestyle factors. Prolonged GERD leads to esophageal inflammation and significantly increases the risk of Barrett’s esophagus (BE) and the subsequent development of esophageal adenocarcinoma (EAC). There is an association between the esophageal microbiome and several esophageal diseases. However, it remains unclear whether the change in microflora leads to esophageal disease, or if this is a side effect of the highly acidic environment created by GERD. Our pilot study aimed to describe oral bacterial biota in patients with GERD and healthy controls from different parts of the esophagus, stomach and duodenum. Detailed microbiome analysis could contribute to early diagnosis and to the application of effective treatment in patients with GERD.
ER  -

Detailed Information on Publication Record