Informační systém MU
SAMEC, Marek, Alena LISKOVA, Lenka KOKLESOVA, Samson Mathews SAMUEL, Radovan MURIN, Pavol ZUBOR, Jan BUJNAK, Taeg Kyu KWON, Dietrich BUSSELBERG, Robert PROSECKÝ, Martin CAPRNDA, Luis RODRIGO, Rachele CICCOCIOPPO, Peter KRUŽLIAK and Peter KUBATKA. The role of plant-derived natural substances as immunomodulatory agents in carcinogenesis. Journal of cancer research and clinical oncology. Germany: Springer-Verlag, 2020, vol. 146, No 12, p. 3137-3154. ISSN 0171-5216. Available from: https://dx.doi.org/10.1007/s00432-020-03424-2.
Other formats:   BibTeX LaTeX RIS
Basic information
Original name The role of plant-derived natural substances as immunomodulatory agents in carcinogenesis
Authors SAMEC, Marek (703 Slovakia), Alena LISKOVA (703 Slovakia), Lenka KOKLESOVA (703 Slovakia), Samson Mathews SAMUEL (356 India), Radovan MURIN (703 Slovakia), Pavol ZUBOR (703 Slovakia), Jan BUJNAK (703 Slovakia), Taeg Kyu KWON (410 Republic of Korea), Dietrich BUSSELBERG (276 Germany), Robert PROSECKÝ (203 Czech Republic, belonging to the institution), Martin CAPRNDA (703 Slovakia), Luis RODRIGO (724 Spain), Rachele CICCOCIOPPO (380 Italy), Peter KRUŽLIAK (703 Slovakia, guarantor, belonging to the institution) and Peter KUBATKA (703 Slovakia).
Edition Journal of cancer research and clinical oncology, Germany, Springer-Verlag, 2020, 0171-5216.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30204 Oncology
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 4.553
RIV identification code RIV/00216224:14110/20:00116763
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1007/s00432-020-03424-2
UT WoS 000577893800001
Keywords in English Cancer; Immunomodulation; Cytokines; Phytochemicals; Preclinical and clinical research
Tags 14110116, 14110121, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 12/5/2021 14:05.
Abstract
The role of immune system in carcinogenesis represents fundamental events associated with cancer eradication; however, tumor evolution is connected with various mechanisms of tumor evasion and progression of cancer. Based on recent evidence, phytochemicals are directly associated with immunomodulation of the innate and adaptive immunity via different mechanisms of action including stimulation and amplification of immune cells, humoral compartments, and associated molecules. This comprehensive study focuses on immunomodulating potential of phytochemicals (mixture in plants or separately such as individual phytochemical) and their impact on regulation of immune response during cancer development, immune tolerance, and immune escape. Clinical application of phytochemicals as modulators of host immunity against cancer may represent perspective approach in anticancer therapy.
Displayed: 21/7/2024 18:22