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@article{1688921, author = {Česká, Katarína and Cesky, Lukas and Ošlejšková, Hana and Aulická, Štefánia}, article_location = {STUTTGART}, article_number = {01}, doi = {http://dx.doi.org/10.1055/s-0040-1718518}, keywords = {epilepsy; Dravet's syndrome; economic study; costs}, language = {eng}, issn = {0174-304X}, journal = {Neuropediatrics}, title = {The Direct Costs of Dravet's Syndrome before and after Diagnosis Assessment}, url = {https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0040-1718518}, volume = {52}, year = {2021} }
TY - JOUR ID - 1688921 AU - Česká, Katarína - Cesky, Lukas - Ošlejšková, Hana - Aulická, Štefánia PY - 2021 TI - The Direct Costs of Dravet's Syndrome before and after Diagnosis Assessment JF - Neuropediatrics VL - 52 IS - 01 SP - 6-11 EP - 6-11 PB - GEORG THIEME VERLAG KG SN - 0174304X KW - epilepsy KW - Dravet's syndrome KW - economic study KW - costs UR - https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0040-1718518 L2 - https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0040-1718518 N2 - The objective of this study was to estimate the direct cost before and after diagnosis assessment in patients with Dravet's syndrome (DS). The basis of the economic study was to calculate the costs of health care before and after diagnosis of DS. We retrospectively evaluated all SCN1A positive patients with phenotype of DS treated in our hospital. Statistical analyses were performed by IBM SPSS Statistics 24.0 software. After the diagnosis of DS, there was a significant decline of health care costs (-85.6%) an average of Euro29.4 +/- 26.1 monthly per patient. We estimated the monthly costs at Euro204.5 +/- 167 (median: Euro193.9, range: Euro35.5-534.4) per patient before DS diagnosis. The major cost was for hospitalization in neurological department: Euro43.3 +/- 52 (median: Euro21.9, range: Euro9.5-179.4) per patient. Minimal cost per patient per months before DS diagnosis was cost of psychological testing/care and complementary rehabilitation (0.13 and 0.6% of total cost). After DS diagnosis, the major cost was focused on nonhospitalization care of patients (64.8%), minimal (Euro0) for genetic testing and major for outpatient care (18%, mean: Euro5.3, median: Euro7). DS results in essential health care utilization and high financial burden before diagnosis elucidation caused by repeated hospitalization and extensive diagnostics tests of "epileptic encephalopathy of unknown etiology." The results of this study point out that early assessment of the diagnosis leads to significant decrease of the financial costs because of adequate therapeutic management and exclusion of redundant diagnostic testing after elucidation of correct diagnosis. ER -
ČESKÁ, Katarína, Lukas CESKY, Hana OŠLEJŠKOVÁ and Štefánia AULICKÁ. The Direct Costs of Dravet's Syndrome before and after Diagnosis Assessment. \textit{Neuropediatrics}. STUTTGART: GEORG THIEME VERLAG KG, 2021, vol.~52, No~01, p.~6-11. ISSN~0174-304X. Available from: https://dx.doi.org/10.1055/s-0040-1718518.
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