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@article{1688927, author = {Chovancova, Barbora and Liskova, Veronika and Babula, Petr and Križanová, Olga}, article_location = {BASEL}, article_number = {9}, doi = {http://dx.doi.org/10.3390/biom10091257}, keywords = {sodium-calcium exchanger; cancer cells; calcium; apoptosis}, language = {eng}, issn = {2218-273X}, journal = {Biomolecules}, title = {Role of Sodium/Calcium Exchangers in Tumors}, url = {https://www.mdpi.com/2218-273X/10/9/1257}, volume = {10}, year = {2020} }
TY - JOUR ID - 1688927 AU - Chovancova, Barbora - Liskova, Veronika - Babula, Petr - Križanová, Olga PY - 2020 TI - Role of Sodium/Calcium Exchangers in Tumors JF - Biomolecules VL - 10 IS - 9 SP - 1-10 EP - 1-10 PB - MDPI SN - 2218273X KW - sodium-calcium exchanger KW - cancer cells KW - calcium KW - apoptosis UR - https://www.mdpi.com/2218-273X/10/9/1257 L2 - https://www.mdpi.com/2218-273X/10/9/1257 N2 - The sodium/calcium exchanger (NCX) is a unique calcium transport system, generally transporting calcium ions out of the cell in exchange for sodium ions. Nevertheless, under special conditions this transporter can also work in a reverse mode, in which direction of the ion transport is inverted-calcium ions are transported inside the cell and sodium ions are transported out of the cell. To date, three isoforms of the NCX have been identified and characterized in humans. Majority of information about the NCX function comes from isoform 1 (NCX1). Although knowledge about NCX function has evolved rapidly in recent years, little is known about these transport systems in cancer cells. This review aims to summarize current knowledge about NCX functions in individual types of cancer cells. ER -
CHOVANCOVA, Barbora, Veronika LISKOVA, Petr BABULA and Olga KRIŽANOVÁ. Role of Sodium/Calcium Exchangers in Tumors. \textit{Biomolecules}. BASEL: MDPI, 2020, vol.~10, No~9, p.~1-10. ISSN~2218-273X. Available from: https://dx.doi.org/10.3390/biom10091257.
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