Well-Blended PCL/PEO Electrospun Nanofibers with Functional
Properties Enhanced by Plasma Processing

J 2020

Well-Blended PCL/PEO Electrospun Nanofibers with Functional Properties Enhanced by Plasma Processing

KUPKA, Vojtěch, Eva DVOŘÁKOVÁ, Anton MANAKHOV, Miroslav MICHLÍČEK, Josef PETRUŠ et. al.

Basic information

Original name

Well-Blended PCL/PEO Electrospun Nanofibers with Functional Properties Enhanced by Plasma Processing

Authors

KUPKA, Vojtěch (203 Czech Republic), Eva DVOŘÁKOVÁ (203 Czech Republic, belonging to the institution), Anton MANAKHOV (643 Russian Federation, belonging to the institution), Miroslav MICHLÍČEK (203 Czech Republic, belonging to the institution), Josef PETRUŠ, Lucy VOJTOVÁ and Lenka ZAJÍČKOVÁ (203 Czech Republic, guarantor, belonging to the institution)

Edition

Polymers, Basel, MDPI, 2020, 2073-4360

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10305 Fluids and plasma physics

Country of publisher

Switzerland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 4.329

RIV identification code

RIV/00216224:14310/20:00114428

Organization unit

Faculty of Science

DOI

http://dx.doi.org/10.3390/polym12061403

UT WoS

000553918200001

Keywords in English

polymer fibers; thin films; plasma enhanced CVD; mechanical properties; SEM

Abstract

V originále

Biodegradable composite nanofibers were electrospun from poly(epsilon-caprolactone) (PCL) and poly(ethylene oxide) (PEO) mixtures dissolved in acetic and formic acids. The variation of PCL:PEO concentration in the polymer blend, from 5:95 to 75:25, revealed the tunability of the hydrolytic stability and mechanical properties of the nanofibrous mats. The degradation rate of PCL/PEO nanofibers can be increased compared to pure PCL, and the mechanical properties can be improved compared to pure PEO. Although PCL and PEO have been previously reported as immiscible, the electrospinning into nanofibers having restricted dimensions (250-450 nm) led to a microscopically mixed PCL/PEO blend. However, the hydrolytic stability and tensile tests revealed the segregation of PCL into few-nanometers-thin fibrils in the PEO matrix of each nanofiber. A synergy phenomenon of increased stiffness appeared for the high concentration of PCL in PCL/PEO nanofibrous mats. The pure PCL and PEO mats had a Young's modulus of about 12 MPa, but the mats made of high concentration PCL in PCL/PEO solution exhibited 2.5-fold higher values. The increase in the PEO content led to faster degradation of mats in water and up to a 20-fold decrease in the nanofibers' ductility. The surface of the PCL/PEO nanofibers was functionalized by an amine plasma polymer thin film that is known to increase the hydrophilicity and attach proteins efficiently to the surface. The combination of different PCL/PEO blends and amine plasma polymer coating enabled us to tune the surface functionality, the hydrolytic stability, and the mechanical properties of biodegradable nanofibrous mats.

Links

GA18-12774S, research and development project

Name: Plazmové polymery připravené na nanovlákenných membránách pro inženýrství cévní tkáně

Investor: Czech Science Foundation

LQ1601, research and development project

Name: CEITEC 2020 (Acronym: CEITEC2020)

Investor: Ministry of Education, Youth and Sports of the CR

Citovat

KUPKA, Vojtěch, Eva DVOŘÁKOVÁ, Anton MANAKHOV, Miroslav MICHLÍČEK, Josef PETRUŠ, Lucy VOJTOVÁ and Lenka ZAJÍČKOVÁ. Well-Blended PCL/PEO Electrospun Nanofibers with Functional Properties Enhanced by Plasma Processing. Polymers. Basel: MDPI, 2020, vol. 12, No 6, p. 1-16. ISSN 2073-4360. Available from: https://dx.doi.org/10.3390/polym12061403.

@article{1689018,
   author = {Kupka, Vojtěch and Dvořáková, Eva and Manakhov, Anton and Michlíček, Miroslav and Petruš, Josef and Vojtová, Lucy and Zajíčková, Lenka},
   article_location = {Basel},
   article_number = {6},
   doi = {http://dx.doi.org/10.3390/polym12061403},
   keywords = {polymer fibers; thin films; plasma enhanced CVD; mechanical properties; SEM},
   language = {eng},
   issn = {2073-4360},
   journal = {Polymers},
   note = {doc. Zajíčková - dle rozhodnutí ředitelů 5.3.2024},
   title = {Well-Blended PCL/PEO Electrospun Nanofibers with Functional Properties Enhanced by Plasma Processing},
   url = {https://www.mdpi.com/2073-4360/12/6/1403},
   volume = {12},
   year = {2020}
}

TY  - JOUR
ID  - 1689018
AU  - Kupka, Vojtěch - Dvořáková, Eva - Manakhov, Anton - Michlíček, Miroslav - Petruš, Josef - Vojtová, Lucy - Zajíčková, Lenka
PY  - 2020
TI  - Well-Blended PCL/PEO Electrospun Nanofibers with Functional Properties Enhanced by Plasma Processing
JF  - Polymers
VL  - 12
IS  - 6
SP  - 1-16
EP  - 1-16
PB  - MDPI
SN  - 20734360
N1  - doc. Zajíčková - dle rozhodnutí ředitelů 5.3.2024
KW  - polymer fibers
KW  - thin films
KW  - plasma enhanced CVD
KW  - mechanical properties
KW  - SEM
UR  - https://www.mdpi.com/2073-4360/12/6/1403
L2  - https://www.mdpi.com/2073-4360/12/6/1403
N2  - Biodegradable composite nanofibers were electrospun from poly(epsilon-caprolactone) (PCL) and poly(ethylene oxide) (PEO) mixtures dissolved in acetic and formic acids. The variation of PCL:PEO concentration in the polymer blend, from 5:95 to 75:25, revealed the tunability of the hydrolytic stability and mechanical properties of the nanofibrous mats. The degradation rate of PCL/PEO nanofibers can be increased compared to pure PCL, and the mechanical properties can be improved compared to pure PEO. Although PCL and PEO have been previously reported as immiscible, the electrospinning into nanofibers having restricted dimensions (250-450 nm) led to a microscopically mixed PCL/PEO blend. However, the hydrolytic stability and tensile tests revealed the segregation of PCL into few-nanometers-thin fibrils in the PEO matrix of each nanofiber. A synergy phenomenon of increased stiffness appeared for the high concentration of PCL in PCL/PEO nanofibrous mats. The pure PCL and PEO mats had a Young's modulus of about 12 MPa, but the mats made of high concentration PCL in PCL/PEO solution exhibited 2.5-fold higher values. The increase in the PEO content led to faster degradation of mats in water and up to a 20-fold decrease in the nanofibers' ductility. The surface of the PCL/PEO nanofibers was functionalized by an amine plasma polymer thin film that is known to increase the hydrophilicity and attach proteins efficiently to the surface. The combination of different PCL/PEO blends and amine plasma polymer coating enabled us to tune the surface functionality, the hydrolytic stability, and the mechanical properties of biodegradable nanofibrous mats.
ER  -

KUPKA, Vojtěch, Eva DVOŘÁKOVÁ, Anton MANAKHOV, Miroslav MICHLÍČEK, Josef PETRUŠ, Lucy VOJTOVÁ and Lenka ZAJÍČKOVÁ. Well-Blended PCL/PEO Electrospun Nanofibers with Functional Properties Enhanced by Plasma Processing. \textit{Polymers}. Basel: MDPI, 2020, vol.~12, No~6, p.~1-16. ISSN~2073-4360. Available from: https://dx.doi.org/10.3390/polym12061403.

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