Generation of humanized bone marrow-like niche for leukemic
xenotransplantation in mice: comparison of biomaterials

a 2020

Generation of humanized bone marrow-like niche for leukemic xenotransplantation in mice: comparison of biomaterials

HERUDKOVÁ, Zdeňka, Filip SOKOL, Jakub VLAŽNÝ, Květoslava LIŠKOVÁ, Leoš KŘEN et. al.

Basic information

Original name

Generation of humanized bone marrow-like niche for leukemic xenotransplantation in mice: comparison of biomaterials

Authors

HERUDKOVÁ, Zdeňka (203 Czech Republic, guarantor, belonging to the institution), Filip SOKOL (203 Czech Republic, belonging to the institution), Jakub VLAŽNÝ (203 Czech Republic, belonging to the institution), Květoslava LIŠKOVÁ (203 Czech Republic, belonging to the institution), Leoš KŘEN (203 Czech Republic, belonging to the institution), Martin REPKO (203 Czech Republic, belonging to the institution), Lucy VOJTOVÁ (203 Czech Republic), Zuzana ŠUSTKOVÁ (203 Czech Republic, belonging to the institution), Zdeněk RÁČIL (203 Czech Republic), Jiří MAYER (203 Czech Republic, belonging to the institution) and Martin ČULEN (703 Slovakia, belonging to the institution)

Edition

25th Congress of European Hematology Association, Amsterdam, Nizozemsko, in HemaSphere, 2020

Other information

Language

English

Type of outcome

Konferenční abstrakt

Field of Study

30205 Hematology

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

RIV identification code

RIV/00216224:14110/20:00116859

Organization unit

Faculty of Medicine

Keywords in English

HUMANIZED BONE MARROW-LIKE NICHE; LEUKEMIC XENOTRANSPLANTATIO

Abstract

V originále

Engraftment of leukemic cells in immunodeficient mice can be improved by incorporation of a humanized bone marrow microenvironment, formed by mesenchymal stromal cells (MSC) and a suitable biomaterial. Various biomaterials ranging from ceramic calcium phosphate to extracellular matrix (ECM) gels were reported so far but their comparison is lacking.

Links

LQ1601, research and development project

Name: CEITEC 2020 (Acronym: CEITEC2020)

Investor: Ministry of Education, Youth and Sports of the CR

Citovat

HERUDKOVÁ, Zdeňka, Filip SOKOL, Jakub VLAŽNÝ, Květoslava LIŠKOVÁ, Leoš KŘEN, Martin REPKO, Lucy VOJTOVÁ, Zuzana ŠUSTKOVÁ, Zdeněk RÁČIL, Jiří MAYER and Martin ČULEN. Generation of humanized bone marrow-like niche for leukemic xenotransplantation in mice: comparison of biomaterials. In 25th Congress of European Hematology Association, Amsterdam, Nizozemsko, in HemaSphere. 2020.

@proceedings{1689777,
   author = {Herudková, Zdeňka and Sokol, Filip and Vlažný, Jakub and Lišková, Květoslava and Křen, Leoš and Repko, Martin and Vojtová, Lucy and Šustková, Zuzana and Ráčil, Zdeněk and Mayer, Jiří and Čulen, Martin},
   booktitle = {25th Congress of European Hematology Association, Amsterdam, Nizozemsko, in HemaSphere},
   keywords = {HUMANIZED BONE MARROW-LIKE NICHE; LEUKEMIC XENOTRANSPLANTATIO},
   language = {eng},
   title = {Generation of humanized bone marrow-like niche for leukemic xenotransplantation in mice: comparison of biomaterials},
   url = {https://library.ehaweb.org/eha/2020/eha25th/293958/martin.culen.generation.of.humanized.bone.marrow-like.niche.for.leukemic.html?f=listing%3D3%2Abrowseby%3D8%2Asortby%3D1%2Amedia%3D1},
   year = {2020}
}

TY  - CONF
ID  - 1689777
AU  - Herudková, Zdeňka - Sokol, Filip - Vlažný, Jakub - Lišková, Květoslava - Křen, Leoš - Repko, Martin - Vojtová, Lucy - Šustková, Zuzana - Ráčil, Zdeněk - Mayer, Jiří - Čulen, Martin
PY  - 2020
TI  - Generation of humanized bone marrow-like niche for leukemic xenotransplantation in mice: comparison of biomaterials
KW  - HUMANIZED BONE MARROW-LIKE NICHE
KW  - LEUKEMIC XENOTRANSPLANTATIO
UR  - https://library.ehaweb.org/eha/2020/eha25th/293958/martin.culen.generation.of.humanized.bone.marrow-like.niche.for.leukemic.html?f=listing%3D3%2Abrowseby%3D8%2Asortby%3D1%2Amedia%3D1
N2  - Engraftment of leukemic cells in immunodeficient mice can be improved by incorporation of a humanized bone marrow microenvironment, formed by mesenchymal stromal cells (MSC) and a suitable biomaterial. Various biomaterials ranging from ceramic calcium phosphate to extracellular matrix (ECM) gels were reported so far but their comparison is lacking.
ER  -

HERUDKOVÁ, Zdeňka, Filip SOKOL, Jakub VLAŽNÝ, Květoslava LIŠKOVÁ, Leoš KŘEN, Martin REPKO, Lucy VOJTOVÁ, Zuzana ŠUSTKOVÁ, Zdeněk RÁČIL, Jiří MAYER and Martin ČULEN. Generation of humanized bone marrow-like niche for leukemic xenotransplantation in mice: comparison of biomaterials. In \textit{25th Congress of European Hematology Association, Amsterdam, Nizozemsko, in HemaSphere}. 2020.

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