HERUDKOVÁ, Zdeňka, Filip SOKOL, Jakub VLAŽNÝ, Květoslava LIŠKOVÁ, Leoš KŘEN, Martin REPKO, Lucy VOJTOVÁ, Zuzana ŠUSTKOVÁ, Zdeněk RÁČIL, Jiří MAYER and Martin ČULEN. Generation of humanized bone marrow-like niche for leukemic xenotransplantation in mice: comparison of biomaterials. In 25th Congress of European Hematology Association, Amsterdam, Nizozemsko, in HemaSphere. 2020.
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Basic information
Original name Generation of humanized bone marrow-like niche for leukemic xenotransplantation in mice: comparison of biomaterials
Authors HERUDKOVÁ, Zdeňka (203 Czech Republic, guarantor, belonging to the institution), Filip SOKOL (203 Czech Republic, belonging to the institution), Jakub VLAŽNÝ (203 Czech Republic, belonging to the institution), Květoslava LIŠKOVÁ (203 Czech Republic, belonging to the institution), Leoš KŘEN (203 Czech Republic, belonging to the institution), Martin REPKO (203 Czech Republic, belonging to the institution), Lucy VOJTOVÁ (203 Czech Republic), Zuzana ŠUSTKOVÁ (203 Czech Republic, belonging to the institution), Zdeněk RÁČIL (203 Czech Republic), Jiří MAYER (203 Czech Republic, belonging to the institution) and Martin ČULEN (703 Slovakia, belonging to the institution).
Edition 25th Congress of European Hematology Association, Amsterdam, Nizozemsko, in HemaSphere, 2020.
Other information
Original language English
Type of outcome Conference abstract
Field of Study 30205 Hematology
Country of publisher Netherlands
Confidentiality degree is not subject to a state or trade secret
WWW URL
RIV identification code RIV/00216224:14110/20:00116859
Organization unit Faculty of Medicine
Keywords in English HUMANIZED BONE MARROW-LIKE NICHE; LEUKEMIC XENOTRANSPLANTATIO
Tags rivok
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 11/5/2021 12:36.
Abstract
Engraftment of leukemic cells in immunodeficient mice can be improved by incorporation of a humanized bone marrow microenvironment, formed by mesenchymal stromal cells (MSC) and a suitable biomaterial. Various biomaterials ranging from ceramic calcium phosphate to extracellular matrix (ECM) gels were reported so far but their comparison is lacking.
Links
LQ1601, research and development projectName: CEITEC 2020 (Acronym: CEITEC2020)
Investor: Ministry of Education, Youth and Sports of the CR
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