Small bowel adenocarcinoma diagnosed by video capsule endoscopy
in a patient with celiac disease: a case report and review of
literature

J 2020

Small bowel adenocarcinoma diagnosed by video capsule endoscopy in a patient with celiac disease: a case report and review of literature

PACKOVÁ, Barbora, Lumír KUNOVSKÝ, Michal EID, Radek KROUPA, Milan DASTYCH et. al.

Basic information

Original name

Small bowel adenocarcinoma diagnosed by video capsule endoscopy in a patient with celiac disease: a case report and review of literature

Name in Czech

Adenokarcinom tenkého střeva diagnostikovaný pomocí video kapslové endoskopie u pacientky s celiakií: kazuistika a přehled literatury

Authors

PACKOVÁ, Barbora (203 Czech Republic, belonging to the institution), Lumír KUNOVSKÝ (203 Czech Republic, belonging to the institution), Michal EID (203 Czech Republic, belonging to the institution), Radek KROUPA (203 Czech Republic, belonging to the institution), Milan DASTYCH (203 Czech Republic, belonging to the institution), Michal ŠENKYŘÍK (203 Czech Republic, belonging to the institution), Tomáš GROLICH (203 Czech Republic, belonging to the institution), Jakub HUSTÝ (203 Czech Republic, belonging to the institution), Petr JABANDŽIEV (203 Czech Republic, belonging to the institution), Václav KUBEŠ (203 Czech Republic, belonging to the institution), Vladimír PROCHÁZKA (203 Czech Republic, belonging to the institution) and Jiří DOLINA (203 Czech Republic, belonging to the institution)

Edition

Vnitřní lékařství, Praha, Ambit Media a.s. 2020, 0042-773X

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30219 Gastroenterology and hepatology

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

RIV identification code

RIV/00216224:14110/20:00117030

Organization unit

Faculty of Medicine

Keywords (in Czech)

adenokarcinom; celiakie; chirurgie; video kapslová endoskopie; tenké střevo

Keywords in English

adenocarcinoma; video capsule endoscopy; celiac disease; small bowel; surgery

Abstract

V originále

Celiac disease is an immune mediated entheropathy triggered by gluten in genetically predisposed individuals. Patients with celiac disease are at a higher risk of gastrointestinal malignancies. Diagnosis at an advance stage is one of the factors of an unfavorable prognosis of these complications. Our patient is a woman who was diagnosed with celiac disease at 53 years of age. After two years on a gluten-free diet she developed sideropenic anemia. No source of bleeding was found on the esophagogastroduodenoscopy or colonoscopy. Video capsule endoscopy revealed exulcerated bleeding stenosis in the jejunum, in front of which the capsule lodged. There were no signs of infiltration on simultaneous CT enterography. The patient was operated on and the infiltration of the jejunum was resected. The specimen was evaluated by a histopathologist as a moderately differentiated adenocarcinoma. Due to the risk factors, the patient received adjuvant chemotherapy. The knowledge of the malignant complications of celiac disease, their risk factors and the possibilities of modern enteroscopic methods could help in the early diagnosis and improvement of the prognosis of these diseases. Due to a lack of data and an absence of guidelines, treatment of a small bowel adenocarcinoma is based on an expert agreement and guidelines for colon cancer. Surgical treatment is the only potentially curative option. For stage II with risk factors and stage III adjuvant chemotherapy should be considered.

Citovat

PACKOVÁ, Barbora, Lumír KUNOVSKÝ, Michal EID, Radek KROUPA, Milan DASTYCH, Michal ŠENKYŘÍK, Tomáš GROLICH, Jakub HUSTÝ, Petr JABANDŽIEV, Václav KUBEŠ, Vladimír PROCHÁZKA and Jiří DOLINA. Small bowel adenocarcinoma diagnosed by video capsule endoscopy in a patient with celiac disease: a case report and review of literature. Vnitřní lékařství. Praha: Ambit Media a.s., 2020, vol. 66, No 7, p. "e39"-"e42", 4 pp. ISSN 0042-773X.

@article{1697581,
   author = {Packová, Barbora and Kunovský, Lumír and Eid, Michal and Kroupa, Radek and Dastych, Milan and Šenkyřík, Michal and Grolich, Tomáš and Hustý, Jakub and Jabandžiev, Petr and Kubeš, Václav and Procházka, Vladimír and Dolina, Jiří},
   article_location = {Praha},
   article_number = {7},
   keywords = {adenocarcinoma; video capsule endoscopy; celiac disease; small bowel; surgery},
   language = {eng},
   issn = {0042-773X},
   journal = {Vnitřní lékařství},
   title = {Small bowel adenocarcinoma diagnosed by video capsule endoscopy in a patient with celiac disease: a case report and review of literature},
   url = {https://www.casopisvnitrnilekarstvi.cz/artkey/vnl-202007-0017_adenokarcinom-tenkeho-streva-diagnostikovany-pomoci-video-kapslove-endoskopie-u-pacientky-s-celiakii-kazuistik.php},
   volume = {66},
   year = {2020}
}

TY  - JOUR
ID  - 1697581
AU  - Packová, Barbora - Kunovský, Lumír - Eid, Michal - Kroupa, Radek - Dastych, Milan - Šenkyřík, Michal - Grolich, Tomáš - Hustý, Jakub - Jabandžiev, Petr - Kubeš, Václav - Procházka, Vladimír - Dolina, Jiří
PY  - 2020
TI  - Small bowel adenocarcinoma diagnosed by video capsule endoscopy in a patient with celiac disease: a case report and review of literature
JF  - Vnitřní lékařství
VL  - 66
IS  - 7
SP  - "e39"-"e42"
EP  - "e39"-"e42"
PB  - Ambit Media a.s.
SN  - 0042773X
KW  - adenocarcinoma
KW  - video capsule endoscopy
KW  - celiac disease
KW  - small bowel
KW  - surgery
UR  - https://www.casopisvnitrnilekarstvi.cz/artkey/vnl-202007-0017_adenokarcinom-tenkeho-streva-diagnostikovany-pomoci-video-kapslove-endoskopie-u-pacientky-s-celiakii-kazuistik.php
L2  - https://www.casopisvnitrnilekarstvi.cz/artkey/vnl-202007-0017_adenokarcinom-tenkeho-streva-diagnostikovany-pomoci-video-kapslove-endoskopie-u-pacientky-s-celiakii-kazuistik.php
N2  - Celiac disease is an immune mediated entheropathy triggered by gluten in genetically predisposed individuals. Patients with celiac disease are at a higher risk of gastrointestinal malignancies. Diagnosis at an advance stage is one of the factors of an unfavorable prognosis of these complications. Our patient is a woman who was diagnosed with celiac disease at 53 years of age. After two years on a gluten-free diet she developed sideropenic anemia. No source of bleeding was found on the esophagogastroduodenoscopy or colonoscopy. Video capsule endoscopy revealed exulcerated bleeding stenosis in the jejunum, in front of which the capsule lodged. There were no signs of infiltration on simultaneous CT enterography. The patient was operated on and the infiltration of the jejunum was resected. The specimen was evaluated by a histopathologist as a moderately differentiated adenocarcinoma. Due to the risk factors, the patient received adjuvant chemotherapy. The knowledge of the malignant complications of celiac disease, their risk factors and the possibilities of modern enteroscopic methods could help in the early diagnosis and improvement of the prognosis of these diseases. Due to a lack of data and an absence of guidelines, treatment of a small bowel adenocarcinoma is based on an expert agreement and guidelines for colon cancer. Surgical treatment is the only potentially curative option. For stage II with risk factors and stage III adjuvant chemotherapy should be considered.
ER  -

PACKOVÁ, Barbora, Lumír KUNOVSKÝ, Michal EID, Radek KROUPA, Milan DASTYCH, Michal ŠENKYŘÍK, Tomáš GROLICH, Jakub HUSTÝ, Petr JABANDŽIEV, Václav KUBEŠ, Vladimír PROCHÁZKA and Jiří DOLINA. Small bowel adenocarcinoma diagnosed by video capsule endoscopy in a patient with celiac disease: a case report and review of literature. \textit{Vnitřní lékařství}. Praha: Ambit Media a.s., 2020, vol.~66, No~7, p.~''e39''-''e42'', 4 pp. ISSN~0042-773X.

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