PACKOVÁ, Barbora, Lumír KUNOVSKÝ, Michal EID, Radek KROUPA, Milan DASTYCH, Michal ŠENKYŘÍK, Tomáš GROLICH, Jakub HUSTÝ, Petr JABANDŽIEV, Václav KUBEŠ, Vladimír PROCHÁZKA and Jiří DOLINA. Small bowel adenocarcinoma diagnosed by video capsule endoscopy in a patient with celiac disease: a case report and review of literature. Vnitřní lékařství. Praha: Ambit Media a.s., 2020, vol. 66, No 7, p. "e39"-"e42", 4 pp. ISSN 0042-773X.
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Basic information
Original name Small bowel adenocarcinoma diagnosed by video capsule endoscopy in a patient with celiac disease: a case report and review of literature
Name in Czech Adenokarcinom tenkého střeva diagnostikovaný pomocí video kapslové endoskopie u pacientky s celiakií: kazuistika a přehled literatury
Authors PACKOVÁ, Barbora (203 Czech Republic, belonging to the institution), Lumír KUNOVSKÝ (203 Czech Republic, belonging to the institution), Michal EID (203 Czech Republic, belonging to the institution), Radek KROUPA (203 Czech Republic, belonging to the institution), Milan DASTYCH (203 Czech Republic, belonging to the institution), Michal ŠENKYŘÍK (203 Czech Republic, belonging to the institution), Tomáš GROLICH (203 Czech Republic, belonging to the institution), Jakub HUSTÝ (203 Czech Republic, belonging to the institution), Petr JABANDŽIEV (203 Czech Republic, belonging to the institution), Václav KUBEŠ (203 Czech Republic, belonging to the institution), Vladimír PROCHÁZKA (203 Czech Republic, belonging to the institution) and Jiří DOLINA (203 Czech Republic, belonging to the institution).
Edition Vnitřní lékařství, Praha, Ambit Media a.s. 2020, 0042-773X.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30219 Gastroenterology and hepatology
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
WWW URL
RIV identification code RIV/00216224:14110/20:00117030
Organization unit Faculty of Medicine
Keywords (in Czech) adenokarcinom; celiakie; chirurgie; video kapslová endoskopie; tenké střevo
Keywords in English adenocarcinoma; video capsule endoscopy; celiac disease; small bowel; surgery
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Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 1/4/2021 13:49.
Abstract
Celiac disease is an immune mediated entheropathy triggered by gluten in genetically predisposed individuals. Patients with celiac disease are at a higher risk of gastrointestinal malignancies. Diagnosis at an advance stage is one of the factors of an unfavorable prognosis of these complications. Our patient is a woman who was diagnosed with celiac disease at 53 years of age. After two years on a gluten-free diet she developed sideropenic anemia. No source of bleeding was found on the esophagogastroduodenoscopy or colonoscopy. Video capsule endoscopy revealed exulcerated bleeding stenosis in the jejunum, in front of which the capsule lodged. There were no signs of infiltration on simultaneous CT enterography. The patient was operated on and the infiltration of the jejunum was resected. The specimen was evaluated by a histopathologist as a moderately differentiated adenocarcinoma. Due to the risk factors, the patient received adjuvant chemotherapy. The knowledge of the malignant complications of celiac disease, their risk factors and the possibilities of modern enteroscopic methods could help in the early diagnosis and improvement of the prognosis of these diseases. Due to a lack of data and an absence of guidelines, treatment of a small bowel adenocarcinoma is based on an expert agreement and guidelines for colon cancer. Surgical treatment is the only potentially curative option. For stage II with risk factors and stage III adjuvant chemotherapy should be considered.
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