Další formáty:
BibTeX
LaTeX
RIS
@article{1699400, author = {Hrdý, Ondřej and Vrbica, Kamil and Straževská, Eva and Suk, Petr and Součková, Lenka and Štěpánová, Radka and Sas, Igor and Gál, Roman}, article_location = {London}, article_number = {1}, doi = {http://dx.doi.org/10.1186/s13063-020-04866-2}, keywords = {Critical Care; Diarrhoea; Enteral nutrition; Gastric residual volume; Intensive care unit.}, language = {eng}, issn = {1745-6215}, journal = {Trials}, title = {Comparison of continuous versus intermittent enteral nutrition in critically ill patients (COINN): study protocol for a randomized comparative effectiveness trial}, url = {https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-020-04866-2}, volume = {21}, year = {2020} }
TY - JOUR ID - 1699400 AU - Hrdý, Ondřej - Vrbica, Kamil - Straževská, Eva - Suk, Petr - Součková, Lenka - Štěpánová, Radka - Sas, Igor - Gál, Roman PY - 2020 TI - Comparison of continuous versus intermittent enteral nutrition in critically ill patients (COINN): study protocol for a randomized comparative effectiveness trial JF - Trials VL - 21 IS - 1 SP - 1-10 EP - 1-10 PB - BioMed Central SN - 17456215 KW - Critical Care KW - Diarrhoea KW - Enteral nutrition KW - Gastric residual volume KW - Intensive care unit. UR - https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-020-04866-2 L2 - https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-020-04866-2 N2 - BackgroundEnteral nutrition is part of the treatment of critically ill patients. Administration of enteral nutrition may be associated with signs of intolerance, such as high gastric residual volumes, diarrhea, and vomiting. Clinical trials regarding the effects of the mode of administration of enteral nutrition on the occurrence of these complications have yielded conflicting results. This trial aims to investigate whether the mode of administration of enteral nutrition affects the time to reach nutritional targets, intolerance, and complications.MethodsCOINN is a randomized, monocentric study for critically ill adult patients receiving enteral nutrition. Patients will be randomly assigned to two groups receiving (1) continuous or (2) intermittent administration of enteral nutrition. Enhancement of enteral nutrition will depend on signs of tolerance, mainly the gastric residual volume. The primary outcome will be the time to reach the energetic target. Secondary outcomes will be the time to reach the protein target, tolerance, complications, hospital and ICU lengths of stay, and 28-day mortality.DiscussionThis trial aims to evaluate whether the mode of application of enteral nutrition affects the time to reach nutritional targets, signs of intolerance, and complications.Trial registrationClinicalTrials.gov NCT03573453. Registered on 29 June 2018. ER -
HRDÝ, Ondřej, Kamil VRBICA, Eva STRAŽEVSKÁ, Petr SUK, Lenka SOUČKOVÁ, Radka ŠTĚPÁNOVÁ, Igor SAS a Roman GÁL. Comparison of continuous versus intermittent enteral nutrition in critically ill patients (COINN): study protocol for a randomized comparative effectiveness trial. \textit{Trials}. London: BioMed Central, roč.~21, č.~1, s.~1-10. ISSN~1745-6215. doi:10.1186/s13063-020-04866-2. 2020.
|