J 2020

The first mitochondrial genomes of endosymbiotic rhabdocoels illustrate evolutionary relaxation of atp8 and genome plasticity in flatworms

MONNENS, Marlies, Sofie THIJS, Andrew G. BRISCOE, Miriam CLARK, Emily Joy FROST et. al.

Basic information

Original name

The first mitochondrial genomes of endosymbiotic rhabdocoels illustrate evolutionary relaxation of atp8 and genome plasticity in flatworms

Authors

MONNENS, Marlies (guarantor), Sofie THIJS, Andrew G. BRISCOE, Miriam CLARK, Emily Joy FROST, D. Tim J. LITTLEWOOD, Mary SEWELL, Karen SMEETS, Tom ARTOIS and Maarten Pieterjan VANHOVE (56 Belgium, belonging to the institution)

Edition

International journal of biological macromolecules, Amsterdam, Elsevier, 2020, 0141-8130

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10613 Zoology

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 6.953

RIV identification code

RIV/00216224:14310/20:00117251

Organization unit

Faculty of Science

DOI

UT WoS

000577936100042

Keywords in English

Platyhelminthes; Rhabdocoela; Genomics; Endosymbiosis; Mitochondrion

Tags

Tags

International impact, Reviewed
Změněno: 7/12/2020 13:24, Mgr. Marie Šípková, DiS.

Abstract

V originále

The first three mitochondrial (mt) genomes of endosymbiotic turbellarian flatworms are characterised for the rhabdocoels Graffilla buccinicola, Syndesmis echinorum and S. kurakaikina. Interspecific comparison of the three newly obtained sequences and the only previously characterised rhabdocoel, the free-living species Bothromesostoma personatum, reveals high mt genomic variability, including numerous rearrangements. The first intrageneric comparison within rhabdocoels shows that gene order is not fully conserved even between congeneric species. Atp8, until recently assumed absent in flatworms, was putatively annotated in two sequences. Selection pressure was tested in a phylogenetic framework and is shown to be significantly relaxed in this and another protein-coding gene: cox1. If present, atp8 appears highly derived in platyhelminths and its functionality needs to be addressed in future research. Our findings for the first time allude to a large degree of undiscovered (mt) genomic plasticity in rhabdocoels. It merits further attention whether this variation is correlated with a symbiotic lifestyle. Our results illustrate that this phenomenon is widespread in flatworms as a whole and not exclusive to the better-studied neodermatans.