CALUORI, Guido, Eva ODEHNALOVÁ, Tomasz JADCZYK, Martin PEŠL, Iveta PAVLOVÁ, Lucia VALÍKOVÁ, Steffen HOLZINGER, Veronika NOVOTNÁ, Vladimír ROTREKL, Aleš HAMPL, Michal CRHA, Dalibor ČERVINKA and Zdeněk STÁREK. AC Pulsed Field Ablation Is Feasible and Safe in Atrial and Ventricular Settings: A Proof-of-Concept Chronic Animal Study. Frontiers in bioengineering and biotechnology. Laussane: Frontiers Media S.A., 2020, vol. 8, DEC 2020, p. 1-14. ISSN 2296-4185. Available from: https://dx.doi.org/10.3389/fbioe.2020.552357.
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Basic information
Original name AC Pulsed Field Ablation Is Feasible and Safe in Atrial and Ventricular Settings: A Proof-of-Concept Chronic Animal Study
Authors CALUORI, Guido (250 France), Eva ODEHNALOVÁ (203 Czech Republic), Tomasz JADCZYK (616 Poland), Martin PEŠL (203 Czech Republic, belonging to the institution), Iveta PAVLOVÁ (203 Czech Republic), Lucia VALÍKOVÁ (703 Slovakia), Steffen HOLZINGER (276 Germany), Veronika NOVOTNÁ (203 Czech Republic), Vladimír ROTREKL (203 Czech Republic, belonging to the institution), Aleš HAMPL (203 Czech Republic, belonging to the institution), Michal CRHA (203 Czech Republic), Dalibor ČERVINKA (203 Czech Republic) and Zdeněk STÁREK (203 Czech Republic, belonging to the institution).
Edition Frontiers in bioengineering and biotechnology, Laussane, Frontiers Media S.A. 2020, 2296-4185.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10606 Microbiology
Country of publisher Switzerland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 5.890
RIV identification code RIV/00216224:14110/20:00117252
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.3389/fbioe.2020.552357
UT WoS 000599322800001
Keywords in English pulsed field ablation; irreversible electroporation (IRE); radiofrequency ablation; atrial fibrillation; ventricular arrhythmia (VA); preclinical cardiology
Tags 14110115, 14110513, 14110517, CF CELLIM, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 10/10/2021 11:20.
Abstract
Pulsed field ablation (PFA) exploits the delivery of short high-voltage shocks to induce cells death via irreversible electroporation. The therapy offers a potential paradigm shift for catheter ablation of cardiac arrhythmia. We designed an AC-burst generator and therapeutic strategy, based on the existing knowledge between efficacy and safety among different pulses. We performed a proof-of-concept chronic animal trial to test the feasibility and safety of our method and technology.
Links
LM2015062, research and development projectName: Národní infrastruktura pro biologické a medicínské zobrazování
Investor: Ministry of Education, Youth and Sports of the CR
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