KINCL, Vladimír, Roman PANOVSKÝ, Martin PEŠL, Jan MÁCHAL, Lenka JUŘÍKOVÁ, Jana HABERLOVÁ and Lucia MASÁROVÁ. Echocardiographic signs of subclinical cardiac function impairment in Duchenne dystrophy gene carriers. Scientific Reports. Berlin: Nature, 2020, vol. 10, No 1, p. 1-6. ISSN 2045-2322. Available from: https://dx.doi.org/10.1038/s41598-020-77882-6. |
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@article{1706276, author = {Kincl, Vladimír and Panovský, Roman and Pešl, Martin and Máchal, Jan and Juříková, Lenka and Haberlová, Jana and Masárová, Lucia}, article_location = {Berlin}, article_number = {1}, doi = {http://dx.doi.org/10.1038/s41598-020-77882-6}, keywords = {Duchenne dystrophy; subclinical cardiac function impairment}, language = {eng}, issn = {2045-2322}, journal = {Scientific Reports}, title = {Echocardiographic signs of subclinical cardiac function impairment in Duchenne dystrophy gene carriers}, url = {https://www.nature.com/articles/s41598-020-77882-6.pdf}, volume = {10}, year = {2020} }
TY - JOUR ID - 1706276 AU - Kincl, Vladimír - Panovský, Roman - Pešl, Martin - Máchal, Jan - Juříková, Lenka - Haberlová, Jana - Masárová, Lucia PY - 2020 TI - Echocardiographic signs of subclinical cardiac function impairment in Duchenne dystrophy gene carriers JF - Scientific Reports VL - 10 IS - 1 SP - 1-6 EP - 1-6 PB - Nature SN - 20452322 KW - Duchenne dystrophy KW - subclinical cardiac function impairment UR - https://www.nature.com/articles/s41598-020-77882-6.pdf L2 - https://www.nature.com/articles/s41598-020-77882-6.pdf N2 - To assess subclinical cardiac function impairment in Duchenne dystrophy (DMD) female carriers. Forty-four female subjects proved as DMD carriers underwent echocardiographic examination including tissue Doppler imaging (TDI) of mitral and tricuspid annulus. Seventeen age-matched healthy female subjects served as controls. A significant differences in peak systolic annular velocity (Sa) between carriers and controls were found for lateral and septal part of the mitral annulus and for tricuspid annulus (0.09 vs. 0.11 m/s, p<0.001, 0.08 vs. 0.09 m/s, p<0.01 and 0.13 vs. 0.14 m/s, p=0.02 respectively). There was also difference in early diastolic velocity (Ea) of the septal part of the mitral annulus (0.11 vs. 0.13 m/s, p=0.03). The subclinical deterioration of systolic function is presented even in asymptomatic DMD female carriers. ER -
KINCL, Vladimír, Roman PANOVSKÝ, Martin PEŠL, Jan MÁCHAL, Lenka JUŘÍKOVÁ, Jana HABERLOVÁ and Lucia MASÁROVÁ. Echocardiographic signs of subclinical cardiac function impairment in Duchenne dystrophy gene carriers. \textit{Scientific Reports}. Berlin: Nature, 2020, vol.~10, No~1, p.~1-6. ISSN~2045-2322. Available from: https://dx.doi.org/10.1038/s41598-020-77882-6.
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