Detailed Information on Publication Record
2019
Maytenus macrocarpa (Ruiz & Pav.) Briq.: Phytochemistry and Pharmacological Activity
MALANÍK, Milan, Jakub TREML, Veronika RJAŠKOVÁ, Karolína TÍŽKOVÁ, Petra KAUCKÁ et. al.Basic information
Original name
Maytenus macrocarpa (Ruiz & Pav.) Briq.: Phytochemistry and Pharmacological Activity
Authors
MALANÍK, Milan, Jakub TREML, Veronika RJAŠKOVÁ, Karolína TÍŽKOVÁ, Petra KAUCKÁ, Ladislav KOKOŠKA, Peter KUBATKA and Karel ŠMEJKAL
Edition
Molecules, BASEL, MDPI, 2019, 1420-3049
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30104 Pharmacology and pharmacy
Confidentiality degree
není předmětem státního či obchodního tajemství
Impact factor
Impact factor: 3.267
Organization unit
Faculty of Pharmacy
UT WoS
000473816900094
Keywords in English
dihydro-beta-agarofuran sesquiterpene; folk medicine; Maytenus macrocarpa; rheumatism; triterpene
Tags
International impact, Reviewed
Změněno: 16/3/2021 11:28, PharmDr. Milan Malaník, Ph.D.
Abstract
V originále
Maytenus macrocarpa (Celastraceae) is a tree native to Amazonia. Its roots, leaves, bark, and combinations of these are used in traditional medicine mainly to treat rheumatism and, to a lesser extent, to heal wounds and to combat bronchitis and diarrhea. To date, mainly triterpenes and dihydro-beta-agarofuran sesquiterpenes were isolated from M. macrocarpa. Extracts and selected pure compounds isolated from the leaves, roots, and stem bark showed antibacterial, antiviral, antiparasitic, anti-inflammatory, and cytotoxic activities in vitro. The aim of this review is to summarize the available ethnobotanical, phytochemical, and pharmacological information about this traditional Amazonian medicinal tree, as well as to attract the attention of phytochemists and pharmacognosists to this potentially interesting source of ethnopharmaceuticals.