MALANÍK, Milan, Jakub TREML, Veronika RJAŠKOVÁ, Karolína TÍŽKOVÁ, Petra KAUCKÁ, Ladislav KOKOŠKA, Peter KUBATKA and Karel ŠMEJKAL. Maytenus macrocarpa (Ruiz & Pav.) Briq.: Phytochemistry and Pharmacological Activity. Online. Molecules. BASEL: MDPI, 2019, vol. 24, No 12, 22 pp. ISSN 1420-3049. Available from: https://dx.doi.org/10.3390/molecules24122288. [citováno 2024-04-23]
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Basic information
Original name Maytenus macrocarpa (Ruiz & Pav.) Briq.: Phytochemistry and Pharmacological Activity
Authors MALANÍK, Milan, Jakub TREML, Veronika RJAŠKOVÁ, Karolína TÍŽKOVÁ, Petra KAUCKÁ, Ladislav KOKOŠKA, Peter KUBATKA and Karel ŠMEJKAL
Edition Molecules, BASEL, MDPI, 2019, 1420-3049.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30104 Pharmacology and pharmacy
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 3.267
Organization unit Faculty of Pharmacy
Doi http://dx.doi.org/10.3390/molecules24122288
UT WoS 000473816900094
Keywords in English dihydro-beta-agarofuran sesquiterpene; folk medicine; Maytenus macrocarpa; rheumatism; triterpene
Tags International impact, Reviewed
Changed by Changed by: PharmDr. Milan Malaník, Ph.D., učo 237248. Changed: 16/3/2021 11:28.
Abstract
Maytenus macrocarpa (Celastraceae) is a tree native to Amazonia. Its roots, leaves, bark, and combinations of these are used in traditional medicine mainly to treat rheumatism and, to a lesser extent, to heal wounds and to combat bronchitis and diarrhea. To date, mainly triterpenes and dihydro-beta-agarofuran sesquiterpenes were isolated from M. macrocarpa. Extracts and selected pure compounds isolated from the leaves, roots, and stem bark showed antibacterial, antiviral, antiparasitic, anti-inflammatory, and cytotoxic activities in vitro. The aim of this review is to summarize the available ethnobotanical, phytochemical, and pharmacological information about this traditional Amazonian medicinal tree, as well as to attract the attention of phytochemists and pharmacognosists to this potentially interesting source of ethnopharmaceuticals.
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