J 2021

Psoas density - an optimal sarcopaenic indicator associated with postoperative complications after colorectal resection for cancer?

PEKAŘOVÁ, Anna, Matej PEKAŘ, Marek SOLTES, Lucia HAVRLENTOVA, Tereza CHOVANCOVA et. al.

Basic information

Original name

Psoas density - an optimal sarcopaenic indicator associated with postoperative complications after colorectal resection for cancer?

Authors

PEKAŘOVÁ, Anna (203 Czech Republic, guarantor, belonging to the institution), Matej PEKAŘ (703 Slovakia, belonging to the institution), Marek SOLTES (703 Slovakia), Lucia HAVRLENTOVA (203 Czech Republic) and Tereza CHOVANCOVA (203 Czech Republic)

Edition

VIDEOSURGERY AND OTHER MINIINVASIVE TECHNIQUES, POZNAN, TERMEDIA PUBLISHING HOUSE LTD, 2021, 1895-4588

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30212 Surgery

Country of publisher

Poland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 1.627

RIV identification code

RIV/00216224:14110/21:00120956

Organization unit

Faculty of Medicine

UT WoS

000624132700012

Keywords in English

complications; colorectal cancer; computed tomography; sarcopaenia; psoas density

Tags

Tags

International impact, Reviewed
Změněno: 2/6/2021 13:17, Mgr. Tereza Miškechová

Abstract

V originále

Introduction: Sarcopaenia seems to be predictive factor for postoperative morbidity and mortality after colorectal resection for cancer. Nevertheless, an ideal sarcopaenic indicator is still to be identified. Aim: To evaluate computed tomography (CT) measured total abdominal muscle area (TAMA), total psoas muscle area (TPA), and psoas density (PD) – previously described sarcopaenia indicators – as possible risk factors for postop- erative complications in patients after curative colon and rectal resections for colorectal cancer. Material and methods: Consecutive patients after elective curative colon or rectal resection for cancer at a sin- gle institution were divided into cohorts with uncomplicated postoperative course or complications Clavien-Dindo grade I-II (Cl-Di 0-II) and complications Clavien-Dindo grade III-V (Cl-Di III-V). Cohorts were statistically tested for significant differences in TAMA, TPA, and PD calculated from preoperative staging CT scans at the level of the third lumbar vertebra. Results: Data of 112 patients were analysed from a prospectively run database; 65 underwent colon and 47 rectal resections. PD was significantly higher in the Cl-Di 0-II cohort compared to the Cl-Di III-V for both colon (42.67 ±6.52 vs. 40.11 ±7.57 HU, p = 0.002) and rectal resections (44.08 ±5.86 vs. 43.03 ±5.70HU, p = 0.016). TAMA and TPA failed to show significant differences. Conclusions: Psoas density is significantly decreased in patients with Clavien-Dindo grade III-V complications after curative resection for colon and rectal cancer. Due to the simplicity and affordability of its assessment from preop- erative staging CT scan, it might be considered an optimal sarcopaenic indicator to be utilised in everyday practice.

Links

MUNI/A/1307/2019, interní kód MU
Name: Kardiovaskulární systém od A do Z (Acronym: KAVASAZ)
Investor: Masaryk University, Category A