The Dynamic Pathosome: A Surrogate for Health and Disease

C 2020

The Dynamic Pathosome: A Surrogate for Health and Disease

LENÁRT, Peter, Martin SCHERINGER and Julie DOBROVOLNÁ

Basic information

Original name

The Dynamic Pathosome: A Surrogate for Health and Disease

Authors

LENÁRT, Peter (703 Slovakia, guarantor, belonging to the institution), Martin SCHERINGER (756 Switzerland, belonging to the institution) and Julie DOBROVOLNÁ (203 Czech Republic, belonging to the institution)

Edition

Neuveden, Explaining Health Across the Sciences, p. 271-288, 18 pp. 2020

Publisher

Springer, Cham

Other information

Language

English

Type of outcome

Kapitola resp. kapitoly v odborné knize

Field of Study

30304 Public and environmental health

Country of publisher

Switzerland

Confidentiality degree

není předmětem státního či obchodního tajemství

Publication form

electronic version available online

References:

URL

RIV identification code

RIV/00216224:14310/20:00117836

Organization unit

Faculty of Science

ISBN

978-3-030-52662-7

DOI

http://dx.doi.org/10.1007/978-3-030-52663-4_16

Keywords in English

Disease; Health; Aging; Individualized medicine; Phenotype trajectories

Abstract

V originále

Regardless of chosen definitions, health, as well as disease, are in their essence only labels describing two enormous groups of phenotypes. Thus, to study either health or disease, we need to understand the factors affecting the development of specific phenotypes. The current paradigm used to explain the development of phenotypes oversimplifies the entire process by omitting the key factor of time. The novel concept of the dynamic pathosome aims to provide a much more detailed picture than the current paradigm. It provides a novel theoretical framework as well as practical applications, but most importantly can change how we perceive health and disease. This chapter reviews the concept of the dynamic pathosome and the benefits it could offer to biomedicine.

Links

EF15_003/0000469, research and development project

Name: Cetocoen Plus

EF16_013/0001761, research and development project

Name: RECETOX RI

LM2015051, research and development project

Name: Centrum pro výzkum toxických látek v prostředí (Acronym: RECETOX RI)

Investor: Ministry of Education, Youth and Sports of the CR

Citovat

LENÁRT, Peter, Martin SCHERINGER and Julie DOBROVOLNÁ. The Dynamic Pathosome: A Surrogate for Health and Disease. Online. In Jonathan ShollSuresh I.S. Rattan. Explaining Health Across the Sciences. Neuveden: Springer, Cham, 2020, p. 271-288. ISBN 978-3-030-52662-7. Available from: https://dx.doi.org/10.1007/978-3-030-52663-4_16.

@inbook{1729230,
   author = {Lenárt, Peter and Scheringer, Martin and Dobrovolná, Julie},
   address = {Neuveden},
   booktitle = {Explaining Health Across the Sciences},
   doi = {http://dx.doi.org/10.1007/978-3-030-52663-4_16},
   editor = {Jonathan ShollSuresh I.S. Rattan},
   keywords = {Disease; Health; Aging; Individualized medicine; Phenotype trajectories},
   howpublished = {elektronická verze "online"},
   language = {eng},
   location = {Neuveden},
   isbn = {978-3-030-52662-7},
   pages = {271-288},
   publisher = {Springer, Cham},
   title = {The Dynamic Pathosome: A Surrogate for Health and Disease},
   url = {https://link.springer.com/chapter/10.1007/978-3-030-52663-4_16},
   year = {2020}
}

TY  - CHAP
ID  - 1729230
AU  - Lenárt, Peter - Scheringer, Martin - Dobrovolná, Julie
PY  - 2020
TI  - The Dynamic Pathosome: A Surrogate for Health and Disease
VL  - Neuveden
PB  - Springer, Cham
CY  - Neuveden
SN  - 9783030526627
KW  - Disease
KW  - Health
KW  - Aging
KW  - Individualized medicine
KW  - Phenotype trajectories
UR  - https://link.springer.com/chapter/10.1007/978-3-030-52663-4_16
L2  - https://link.springer.com/chapter/10.1007/978-3-030-52663-4_16
N2  - Regardless of chosen definitions, health, as well as disease, are in their essence only labels describing two enormous groups of phenotypes. Thus, to study either health or disease, we need to understand the factors affecting the development of specific phenotypes. The current paradigm used to explain the development of phenotypes oversimplifies the entire process by omitting the key factor of time. The novel concept of the dynamic pathosome aims to provide a much more detailed picture than the current paradigm. It provides a novel theoretical framework as well as practical applications, but most importantly can change how we perceive health and disease. This chapter reviews the concept of the dynamic pathosome and the benefits it could offer to biomedicine.
ER  -

LENÁRT, Peter, Martin SCHERINGER and Julie DOBROVOLNÁ. The Dynamic Pathosome: A Surrogate for Health and Disease. Online. In Jonathan ShollSuresh I.S. Rattan. \textit{Explaining Health Across the Sciences}. Neuveden: Springer, Cham, 2020, p.~271-288. ISBN~978-3-030-52662-7. Available from: https://dx.doi.org/10.1007/978-3-030-52663-4\_{}16.

Detailed Information on Publication Record