Oral Complications of ICU Patients with COVID-19: Case-Series
and Review of Two Hundred Ten Cases

J 2021

Oral Complications of ICU Patients with COVID-19: Case-Series and Review of Two Hundred Ten Cases

HOCKOVA, Barbora, Abanoub RIAD, Jozef VALKY, Zuzana ŠULAJOVÁ, Adam STEBEL et. al.

Basic information

Original name

Oral Complications of ICU Patients with COVID-19: Case-Series and Review of Two Hundred Ten Cases

Authors

HOCKOVA, Barbora, Abanoub RIAD (818 Egypt, guarantor, belonging to the institution), Jozef VALKY, Zuzana ŠULAJOVÁ, Adam STEBEL, Rastislav SLÁVIK, Zuzana BEČKOVÁ, Andrea POKORNÁ (203 Czech Republic, belonging to the institution), Jitka KLUGAROVÁ (203 Czech Republic, belonging to the institution) and Miloslav KLUGAR (203 Czech Republic, belonging to the institution)

Edition

Journal of Clinical Medicine, Basel, MDPI, 2021, 2077-0383

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30218 General and internal medicine

Country of publisher

Switzerland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 4.964

RIV identification code

RIV/00216224:14110/21:00121097

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.3390/jcm10040581

UT WoS

000623996700001

Keywords in English

candidiasis; COVID-19; critical care; macroglossia; oral manifestations; pressure ulcer; prone position

Abstract

V originále

ackground: The critically ill patients suffering from coronavirus disease (COVID-19) and admitted to the intensive care units (ICUs) are susceptible to a wide array of complications that can be life-threatening or impose them to long-term complications. The COVID-19 oral mucocutaneous complications require multidisciplinary management and research for their pathophysiological course and epidemiological significance; therefore, the objective of this study was to evaluate the prevalence and characteristics of the critically ill COVID-19 patients with oral complications. Methods: We described the clinical and microbiological characteristics of the critically ill COVID-19 patients in our ICU department (Banska Bystrica, Slovakia). In addition, we reviewed the current body of evidence in Ovid MEDLINE®, Embase, Cochrane Library, and Google Scholar for the oral mucocutaneous complications of ICU patients with COVID-19. Results: Three out of nine critically ill patients (33.3%) in our ICU department presented with oral complications including haemorrhagic ulcers and necrotic ulcers affecting the lips and tongue. The microbiological assessment revealed the presence of opportunistic pathogens, confirming the possibility of co-infection. On reviewing the current literature, two hundred ten critically ill patients were reported to have oral complications due to their stay in the ICU setting. Perioral pressure ulcers were the most common complication, followed by oral candidiasis, herpetic and haemorrhagic ulcers, and acute onset macroglossia. The prolonged prone positioning and mechanical ventilation devices were the primary risk factors for those oral complications, in addition to the immunosuppressive drugs. Conclusions: The multidisciplinary approach is strongly advocated for monitoring and management of COVID-19 patients, thus implying that dermatology and oral healthcare specialists and nurses should be integrated within the ICU teams.

Links

LTC20031, research and development project

Name: Towards an International Network for Evidence-based Research in Clinical Health Research in the Czech Republic

Investor: Ministry of Education, Youth and Sports of the CR, INTER-COST

MUNI/A/1608/2020, interní kód MU

Name: Prohlubování znalostí v oblasti zdravotních rizik a benefitů výživy, prostředí a životního stylu III

Investor: Masaryk University

MUNI/IGA/1543/2020, interní kód MU

Name: Evidence-based Practice of Healthcare Professionals and Students in the Czech Republic (Acronym: Evidence-Based Practice in Czechia)

Investor: Masaryk University

Citovat

HOCKOVA, Barbora, Abanoub RIAD, Jozef VALKY, Zuzana ŠULAJOVÁ, Adam STEBEL, Rastislav SLÁVIK, Zuzana BEČKOVÁ, Andrea POKORNÁ, Jitka KLUGAROVÁ and Miloslav KLUGAR. Oral Complications of ICU Patients with COVID-19: Case-Series and Review of Two Hundred Ten Cases. Journal of Clinical Medicine. Basel: MDPI, 2021, vol. 10, No 4, p. 1-14. ISSN 2077-0383. Available from: https://dx.doi.org/10.3390/jcm10040581.

@article{1738216,
   author = {Hockova, Barbora and Riad, Abanoub and Valky, Jozef and Šulajová, Zuzana and Stebel, Adam and Slávik, Rastislav and Bečková, Zuzana and Pokorná, Andrea and Klugarová, Jitka and Klugar, Miloslav},
   article_location = {Basel},
   article_number = {4},
   doi = {http://dx.doi.org/10.3390/jcm10040581},
   keywords = {candidiasis; COVID-19; critical care; macroglossia; oral manifestations; pressure ulcer; prone position},
   language = {eng},
   issn = {2077-0383},
   journal = {Journal of Clinical Medicine},
   title = {Oral Complications of ICU Patients with COVID-19: Case-Series and Review of Two Hundred Ten Cases},
   url = {https://www.mdpi.com/2077-0383/10/4/581},
   volume = {10},
   year = {2021}
}

TY  - JOUR
ID  - 1738216
AU  - Hockova, Barbora - Riad, Abanoub - Valky, Jozef - Šulajová, Zuzana - Stebel, Adam - Slávik, Rastislav - Bečková, Zuzana - Pokorná, Andrea - Klugarová, Jitka - Klugar, Miloslav
PY  - 2021
TI  - Oral Complications of ICU Patients with COVID-19: Case-Series and Review of Two Hundred Ten Cases
JF  - Journal of Clinical Medicine
VL  - 10
IS  - 4
SP  - 1-14
EP  - 1-14
PB  - MDPI
SN  - 20770383
KW  - candidiasis
KW  - COVID-19
KW  - critical care
KW  - macroglossia
KW  - oral manifestations
KW  - pressure ulcer
KW  - prone position
UR  - https://www.mdpi.com/2077-0383/10/4/581
L2  - https://www.mdpi.com/2077-0383/10/4/581
N2  - ackground: The critically ill patients suffering from coronavirus disease (COVID-19) and admitted to the intensive care units (ICUs) are susceptible to a wide array of complications that can be life-threatening or impose them to long-term complications. The COVID-19 oral mucocutaneous complications require multidisciplinary management and research for their pathophysiological course and epidemiological significance; therefore, the objective of this study was to evaluate the prevalence and characteristics of the critically ill COVID-19 patients with oral complications. Methods: We described the clinical and microbiological characteristics of the critically ill COVID-19 patients in our ICU department (Banska Bystrica, Slovakia). In addition, we reviewed the current body of evidence in Ovid MEDLINE®, Embase, Cochrane Library, and Google Scholar for the oral mucocutaneous complications of ICU patients with COVID-19. Results: Three out of nine critically ill patients (33.3%) in our ICU department presented with oral complications including haemorrhagic ulcers and necrotic ulcers affecting the lips and tongue. The microbiological assessment revealed the presence of opportunistic pathogens, confirming the possibility of co-infection. On reviewing the current literature, two hundred ten critically ill patients were reported to have oral complications due to their stay in the ICU setting. Perioral pressure ulcers were the most common complication, followed by oral candidiasis, herpetic and haemorrhagic ulcers, and acute onset macroglossia. The prolonged prone positioning and mechanical ventilation devices were the primary risk factors for those oral complications, in addition to the immunosuppressive drugs. Conclusions: The multidisciplinary approach is strongly advocated for monitoring and management of COVID-19 patients, thus implying that dermatology and oral healthcare specialists and nurses should be integrated within the ICU teams.
ER  -

HOCKOVA, Barbora, Abanoub RIAD, Jozef VALKY, Zuzana ŠULAJOVÁ, Adam STEBEL, Rastislav SLÁVIK, Zuzana BEČKOVÁ, Andrea POKORNÁ, Jitka KLUGAROVÁ and Miloslav KLUGAR. Oral Complications of ICU Patients with COVID-19: Case-Series and Review of Two Hundred Ten Cases. \textit{Journal of Clinical Medicine}. Basel: MDPI, 2021, vol.~10, No~4, p.~1-14. ISSN~2077-0383. Available from: https://dx.doi.org/10.3390/jcm10040581.

Detailed Information on Publication Record