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@article{1738520, author = {Hořavová, Hana and Gajdziok, Jan and Vetchý, David}, article_location = {Praha}, article_number = {5}, keywords = {liposomes; lung application; spray drying; lyophylization; dry powder formulations; protectants}, language = {cze}, issn = {0009-2770}, journal = {CHEMICKÉ LISTY}, title = {Typy a příprava lipozomálních přípravků pro plicní podání}, url = {http://www.chemicke-listy.cz/ojs3/index.php/chemicke-listy/article/view/3599}, volume = {114}, year = {2020} }
TY - JOUR ID - 1738520 AU - Hořavová, Hana - Gajdziok, Jan - Vetchý, David PY - 2020 TI - Typy a příprava lipozomálních přípravků pro plicní podání JF - CHEMICKÉ LISTY VL - 114 IS - 5 SP - 322-328 EP - 322-328 PB - Česká společnost chemická SN - 00092770 KW - liposomes KW - lung application KW - spray drying KW - lyophylization KW - dry powder formulations KW - protectants UR - http://www.chemicke-listy.cz/ojs3/index.php/chemicke-listy/article/view/3599 N2 - The use of liposomes as carriers for different types of drugs in formulations to be administered to the lungs brings a number of advantages, including the possibility of controlled release, prolongation of retention at the site of action or reduced systemic exposure. However, the main disadvantage of liposomal suspensions is their physical and chemical instability. Therefore, they are preferably converted to dry powders by several drying technologies. In doing so, it is necessary to include specific excipients in the formulation, in particular protectants (saccharides), protecting liposomes from changes during these processes. ER -
HOŘAVOVÁ, Hana, Jan GAJDZIOK and David VETCHÝ. Typy a příprava lipozomálních přípravků pro plicní podání (Types and Preparation of Liposomal Formulations for Pulmonary Administration). \textit{CHEMICKÉ LISTY}. Praha: Česká společnost chemická, 2020, vol.~114, No~5, p.~322-328. ISSN~0009-2770.
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