J 2022

Primary percutaneous coronary intervention is appropriate in transient ST-elevation myocardial infarction

KOC, Lumír, Monika MIKOLÁŠKOVÁ, Tomáš NOVOTNÝ, Jiří PAŘENICA, Jan KAŇOVSKÝ et. al.

Basic information

Original name

Primary percutaneous coronary intervention is appropriate in transient ST-elevation myocardial infarction

Authors

KOC, Lumír (203 Czech Republic, belonging to the institution), Monika MIKOLÁŠKOVÁ (703 Slovakia, belonging to the institution), Tomáš NOVOTNÝ (203 Czech Republic, belonging to the institution), Jiří PAŘENICA (203 Czech Republic, belonging to the institution), Jan KAŇOVSKÝ (203 Czech Republic, belonging to the institution), Tomáš ONDRÚŠ (703 Slovakia, belonging to the institution), Mária HOLICKÁ (703 Slovakia, belonging to the institution), Martin POLOCZEK (203 Czech Republic), Jiří JARKOVSKÝ (203 Czech Republic, belonging to the institution), Marek MALÍK (203 Czech Republic, belonging to the institution) and Petr KALA (203 Czech Republic, guarantor, belonging to the institution)

Edition

Biomedical Papers, Olomouc, PALACKY UNIV, MEDICAL FAC, 2022, 1213-8118

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30201 Cardiac and Cardiovascular systems

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 0.900

RIV identification code

RIV/00216224:14110/22:00124904

Organization unit

Faculty of Medicine

DOI

UT WoS

000731339500001

Keywords in English

STEMI; Primary PCI; ST-segment resolution; TSTEMI; 5-year survival

Tags

Tags

International impact, Reviewed
Změněno: 20/7/2022 09:24, Mgr. Tereza Miškechová

Abstract

V originále

ntroduction: Reperfusion therapy by primary percutaneous coronary intervention (PPCI) is generally indicated in patients suffering from acute myocardial infarction (MI) with ST-segment elevation (STEMI). Prior to hospital admission, full ST-segment resolution (fSTR) may occur. Optimal management of such patients with transient STEMI (TSTEMI) is potentially challenging. Our aim was to evaluate the hypothesis that in TSTEMI patients, patency of infarct related artery (IRA) is achieved before PPCI, and to compare the outcome of TSTEMI and STEMI patients during a prolonged follow-up. Material and Methods: Three hundred consecutive adult STEMI patients were referred to catheterization laboratory. In all patients, standard 12 lead ECGs were obtained both at the time of the first medical contact, and on catheterization laboratory admission. Results: TSTEMI occurred in 20 patients (6.7%). Despite fSTR (isoelectric ST segment), occluded IRA was found in 5 of these patients (25%). Pre-PPCI TIMI flow grade 2 was found in 6 TSTEMI patients (30%). Troponin T value at 24 h after symptom onset was lower in the TSTEMI group (1.8±2.5 mg/L vs. 3.6±3.5 mg/L, P=0.008). These patients also had a lower value of brain natriuretic peptide (156.3±119.5 ng/L vs. 438.5±429.0 ng/L, P<0.001) and higher left ventricular ejection fraction (59.9±6.3% vs. 51.6±10.2%, P<0.001). All patients were followed for a median of 5.6 years during which the overall survival did not differ between the TSTEMI and STEMI groups.