Therapeutic potential of prenylated stilbenoid macasiamenene F
through its anti-inflammatory and cytoprotective effects on
LPS-challenged monocytes and microglia

J 2020

Therapeutic potential of prenylated stilbenoid macasiamenene F through its anti-inflammatory and cytoprotective effects on LPS-challenged monocytes and microglia

LELÁKOVÁ, Veronika, Sophie BÉRAUD-DUFOUR, Jan HOŠEK, Karel ŠMEJKAL, Vilailak PRACHYAWARAKORN et. al.

Basic information

Original name

Therapeutic potential of prenylated stilbenoid macasiamenene F through its anti-inflammatory and cytoprotective effects on LPS-challenged monocytes and microglia

Authors

LELÁKOVÁ, Veronika (703 Slovakia, guarantor, belonging to the institution), Sophie BÉRAUD-DUFOUR (250 France), Jan HOŠEK (203 Czech Republic, belonging to the institution), Karel ŠMEJKAL (203 Czech Republic, belonging to the institution), Vilailak PRACHYAWARAKORN, Phanruethai PAILEE, Catherine WIDMANN (250 France), Jiří VÁCLAVÍK (203 Czech Republic, belonging to the institution), Thierry COPPOLA (250 France), Jean MAZELLA (250 France), Nicolas BLONDEAU (250 France) and Catherine HEURTEAUX (250 France)

Edition

JOURNAL OF ETHNOPHARMACOLOGY, CLARE, ELSEVIER IRELAND LTD, 2020, 0378-8741

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30104 Pharmacology and pharmacy

Country of publisher

Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 4.360

RIV identification code

RIV/00216224:14160/20:00114749

Organization unit

Faculty of Pharmacy

DOI

http://dx.doi.org/10.1016/j.jep.2020.113147

UT WoS

000571141100002

Keywords in English

Natural stilbenoids; Neuroinflammation; Microglia; Monocytes; Prenyl

Abstract

V originále

Ethnopharmacological relevance: Macaranga Thou. (Euphorbiaceae) is a large genus that comprises over 300 species distributed between Western Africa and the islands of the South Pacific. Plants of this genus have a long-standing history of use in traditional medicine for different purposes, including the treatment of inflammation. Fresh and dried leaves of certain Macaranga species (e.g. M. tanarius (L.) Müll.Arg.), have been used to treat cuts, bruises, boils, swellings, sores and covering of wounds in general. Several reports described Macaranga spp. being a rich source of polyphenols, such as prenylated stilbenoids and flavonoids, mostly responsible for its biological activity. Similarly, an abundant content of prenylated stilbenes was also described in M. siamensis S.J.Davies, species recently identified (2001) in Thailand. While the respective biological activity of the prenylated stilbenes from M. siamensis was poorly investigated to date, our recent study pointed out the interest as the natural source of several novel anti-inflammatory stilbenoids isolated from this species.

Links

GA16-07193S, research and development project

Name: Protizánětlivá aktivita vybraných stilbenů, 2-arylbenzofuranů a jejich metabolitů

Citovat

LELÁKOVÁ, Veronika, Sophie BÉRAUD-DUFOUR, Jan HOŠEK, Karel ŠMEJKAL, Vilailak PRACHYAWARAKORN, Phanruethai PAILEE, Catherine WIDMANN, Jiří VÁCLAVÍK, Thierry COPPOLA, Jean MAZELLA, Nicolas BLONDEAU and Catherine HEURTEAUX. Therapeutic potential of prenylated stilbenoid macasiamenene F through its anti-inflammatory and cytoprotective effects on LPS-challenged monocytes and microglia. JOURNAL OF ETHNOPHARMACOLOGY. CLARE: ELSEVIER IRELAND LTD, 2020, vol. 263, No 263, p. 1-14. ISSN 0378-8741. Available from: https://dx.doi.org/10.1016/j.jep.2020.113147.

@article{1745798,
   author = {Leláková, Veronika and BéraudandDufour, Sophie and Hošek, Jan and Šmejkal, Karel and Prachyawarakorn, Vilailak and Pailee, Phanruethai and Widmann, Catherine and Václavík, Jiří and Coppola, Thierry and Mazella, Jean and Blondeau, Nicolas and Heurteaux, Catherine},
   article_location = {CLARE},
   article_number = {263},
   doi = {http://dx.doi.org/10.1016/j.jep.2020.113147},
   keywords = {Natural stilbenoids; Neuroinflammation; Microglia; Monocytes; Prenyl},
   language = {eng},
   issn = {0378-8741},
   journal = {JOURNAL OF ETHNOPHARMACOLOGY},
   title = {Therapeutic potential of prenylated stilbenoid macasiamenene F through its anti-inflammatory and cytoprotective effects on LPS-challenged monocytes and microglia},
   url = {https://www.sciencedirect.com/science/article/pii/S0378874120330294?via%3Dihub},
   volume = {263},
   year = {2020}
}

TY  - JOUR
ID  - 1745798
AU  - Leláková, Veronika - Béraud-Dufour, Sophie - Hošek, Jan - Šmejkal, Karel - Prachyawarakorn, Vilailak - Pailee, Phanruethai - Widmann, Catherine - Václavík, Jiří - Coppola, Thierry - Mazella, Jean - Blondeau, Nicolas - Heurteaux, Catherine
PY  - 2020
TI  - Therapeutic potential of prenylated stilbenoid macasiamenene F through its anti-inflammatory and cytoprotective effects on LPS-challenged monocytes and microglia
JF  - JOURNAL OF ETHNOPHARMACOLOGY
VL  - 263
IS  - 263
SP  - 1-14
EP  - 1-14
PB  - ELSEVIER IRELAND LTD
SN  - 03788741
KW  - Natural stilbenoids
KW  - Neuroinflammation
KW  - Microglia
KW  - Monocytes
KW  - Prenyl
UR  - https://www.sciencedirect.com/science/article/pii/S0378874120330294?via%3Dihub
N2  - Ethnopharmacological relevance: Macaranga Thou. (Euphorbiaceae) is a large genus that comprises over 300 species distributed between Western Africa and the islands of the South Pacific. Plants of this genus have a long-standing history of use in traditional medicine for different purposes, including the treatment of inflammation. Fresh and dried leaves of certain Macaranga species (e.g. M. tanarius (L.) Müll.Arg.), have been used to treat cuts, bruises, boils, swellings, sores and covering of wounds in general. Several reports described Macaranga spp. being a rich source of polyphenols, such as prenylated stilbenoids and flavonoids, mostly responsible for its biological activity. Similarly, an abundant content of prenylated stilbenes was also described in M. siamensis S.J.Davies, species recently identified (2001) in Thailand. While the respective biological activity of the prenylated stilbenes from M. siamensis was poorly investigated to date, our recent study pointed out the interest as the natural source of several novel anti-inflammatory stilbenoids isolated from this species.
ER  -

LELÁKOVÁ, Veronika, Sophie BÉRAUD-DUFOUR, Jan HOŠEK, Karel ŠMEJKAL, Vilailak PRACHYAWARAKORN, Phanruethai PAILEE, Catherine WIDMANN, Jiří VÁCLAVÍK, Thierry COPPOLA, Jean MAZELLA, Nicolas BLONDEAU and Catherine HEURTEAUX. Therapeutic potential of prenylated stilbenoid macasiamenene F through its anti-inflammatory and cytoprotective effects on LPS-challenged monocytes and microglia. \textit{JOURNAL OF ETHNOPHARMACOLOGY}. CLARE: ELSEVIER IRELAND LTD, 2020, vol.~263, No~263, p.~1-14. ISSN~0378-8741. Available from: https://dx.doi.org/10.1016/j.jep.2020.113147.

Detailed Information on Publication Record