| SPACEK, J., N. KARALKAR, Miroslav FOJTA, J. WANG and S.A. BENNER. Electrochemical reduction and oxidation of eight unnatural 2 '-deoxynucleosides at a pyrolytic graphite electrode. Electrochimica Acta. OXFORD: Elsevier, 2020, vol. 362, DEC, p. 137210-137217. ISSN 0013-4686. Available from: https://dx.doi.org/10.1016/j.electacta.2020.137210. |
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@article{1748077,
author = {Spacek, J. and Karalkar, N. and Fojta, Miroslav and Wang, J. and Benner, S.A.},
article_location = {OXFORD},
article_number = {DEC},
doi = {http://dx.doi.org/10.1016/j.electacta.2020.137210},
keywords = {Electrochemistry; Electrochemical oxidation; Electrochemical reduction; Pyrolytic graphite; Unnatural DNA},
language = {eng},
issn = {0013-4686},
journal = {Electrochimica Acta},
title = {Electrochemical reduction and oxidation of eight unnatural 2 '-deoxynucleosides at a pyrolytic graphite electrode},
url = {https://www.sciencedirect.com/science/article/pii/S0013468620316030?via%3Dihub},
volume = {362},
year = {2020}
}
TY - JOUR
ID - 1748077
AU - Spacek, J. - Karalkar, N. - Fojta, Miroslav - Wang, J. - Benner, S.A.
PY - 2020
TI - Electrochemical reduction and oxidation of eight unnatural 2 '-deoxynucleosides at a pyrolytic graphite electrode
JF - Electrochimica Acta
VL - 362
IS - DEC
SP - 137210
EP - 137210
PB - Elsevier
SN - 00134686
KW - Electrochemistry
KW - Electrochemical oxidation
KW - Electrochemical reduction
KW - Pyrolytic graphite
KW - Unnatural DNA
UR - https://www.sciencedirect.com/science/article/pii/S0013468620316030?via%3Dihub
N2 - Recently we showed the reduction and oxidation of six natural 2'-deoxynucleosides in the presence of the ambient oxygen using the very broad potential window of a pyrolytic graphite electrode (PGE). Using the same procedure, 2'-deoxynucleoside analogs (dNs) that are parts of an artificially expanded genetic information system (AEGIS) were analyzed. Seven of the eight tested AEGIS dNs provided specific signals (voltammetric redox peaks). These signals, described here for the first time, will be used in future work to analyze DNA built from expanded genetic alphabets, helping to further develop AEGIS technology and its applications. Comparison of the electrochemical behavior of unnatural dNs with the previously documented behaviors of natural dNs also provides insights into the mechanisms of their respective redox processes. (C) 2020 Elsevier Ltd. All rights reserved.
ER -
SPACEK, J., N. KARALKAR, Miroslav FOJTA, J. WANG and S.A. BENNER. Electrochemical reduction and oxidation of eight unnatural 2 '-deoxynucleosides at a pyrolytic graphite electrode. \textit{Electrochimica Acta}. OXFORD: Elsevier, 2020, vol.~362, DEC, p.~137210-137217. ISSN~0013-4686. Available from: https://dx.doi.org/10.1016/j.electacta.2020.137210.
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