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@article{1752481,
author = {Džatko, Šimon and Fiala, Radovan and HanselandHertsch, R. and Trantírková, Silvie and Trantírek, Lukáš},
article_location = {CAMBRIDGE},
article_number = {2020},
doi = {http://dx.doi.org/10.1039/9781788013079},
keywords = {DNA; guanine quadruplex; nucleic acid; water},
language = {eng},
issn = {2044-253X},
journal = {IN-CELL NMR SPECTROSCOPY: FROM MOLECULAR SCIENCES TO CELL BIOLOGY},
title = {In-cell NMR Spectroscopy of Nucleic Acids},
url = {https://pubs.rsc.org/en/content/chapter/bk9781788012171-00272/978-1-78801-217-1},
volume = {21},
year = {2020}
}
TY - JOUR
ID - 1752481
AU - Džatko, Šimon - Fiala, Radovan - Hansel-Hertsch, R. - Trantírková, Silvie - Trantírek, Lukáš
PY - 2020
TI - In-cell NMR Spectroscopy of Nucleic Acids
JF - IN-CELL NMR SPECTROSCOPY: FROM MOLECULAR SCIENCES TO CELL BIOLOGY
VL - 21
IS - 2020
SP - 272-297
EP - 272-297
PB - ROYAL SOC CHEMISTRY
SN - 2044253X
KW - DNA
KW - guanine quadruplex
KW - nucleic acid
KW - water
UR - https://pubs.rsc.org/en/content/chapter/bk9781788012171-00272/978-1-78801-217-1
N2 - The structure, dynamics, and interactions of nucleic acids, in particular DNAs, sensitively respond to a broad range of environmental factors, many of them being natively present in the intracellular space. In-cell NMR is a tailored adaptation of conventional high-resolution nuclear magnetic resonance spectroscopy that permits characterization of stereochemical features of nucleic acids directly in living cells. Here we review recent advances and applications of in-cell NMR to nucleic acids. The limitations of this method as well as the general considerations, comprising of critical factors to be accounted for during the planning of in-cell NMR experiments, as well as during the interpretation of in-cell NMR data, are discussed.
ER -
DŽATKO, Šimon, Radovan FIALA, R. HANSEL-HERTSCH, Silvie TRANTÍRKOVÁ and Lukáš TRANTÍREK. In-cell NMR Spectroscopy of Nucleic Acids. \textit{IN-CELL NMR SPECTROSCOPY: FROM MOLECULAR SCIENCES TO CELL BIOLOGY}. CAMBRIDGE: ROYAL SOC CHEMISTRY, 2020, vol.~21, No~2020, p.~272-297. ISSN~2044-253X. Available from: https://dx.doi.org/10.1039/9781788013079.
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