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REKTOROVÁ, Irena, Patrícia KLOBUŠIAKOVÁ, Zuzana BALÁŽOVÁ, Sylvie KROPÁČOVÁ, Alžběta ŠEJNOHA MINSTEROVÁ, Roman GRMELA, Alena SKOTÁKOVÁ and Ivan REKTOR. Brain structure changes in nondemented seniors after six-month dance-exercise intervention. Acta Neurologica Scandinavica. Hoboken: WILEY-BLACKWELL, 2020, vol. 141, No 1, p. 90-97. ISSN 0001-6314. Available from: https://dx.doi.org/10.1111/ane.13181.

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TY  - JOUR
ID  - 1752492
AU  - Rektorová, Irena - Klobušiaková, Patrícia - Balážová, Zuzana - Kropáčová, Sylvie - Šejnoha Minsterová, Alžběta - Grmela, Roman - Skotáková, Alena - Rektor, Ivan
PY  - 2020
TI  - Brain structure changes in nondemented seniors after six-month dance-exercise intervention
JF  - Acta Neurologica Scandinavica
VL  - 141
IS  - 1
SP  - 90-97
EP  - 90-97
PB  - WILEY-BLACKWELL
SN  - 00016314
KW  - cognitive
KW  - cortical thickness
KW  - dance-exercise intervention
KW  - DTI
KW  - healthy seniors
KW  - lateral temporo-occipital cortex
KW  - mild cognitive impairment
KW  - MRI
UR  - https://onlinelibrary.wiley.com/doi/full/10.1111/ane.13181
N2  - Objectives To evaluate effects of a six-month intensive dance-exercise intervention (DI) on cognition and brain structure in a mixed group of healthy seniors and people with mild cognitive impairment. Methods Subjects (aged > 60 years with no dementia or depression) were randomly assigned to either a DI group or a life as usual (LAU) group. Detailed neuropsychological testing, measures of physical fitness and brain MRI encompassing T1 structural and diffusion tensor imaging (DTI) were performed at baseline and after 6 months. We assessed changes in cortical thickness and DTI parameters derived from tract-based spatial statistics. Results Altogether 62 individuals (n = 31 in the DI group) completed the protocol. The groups were matched for their demographic and clinical variables. After 6 months, we found significant cortical thickening in the right inferior temporal, fusiform and lateral occipital regions in the dancers compared to controls. Significant increases of radial and mean diffusivity were observed in various white matter tracts in the dancers; however, no differences were observed between the DI and LAU groups. The DI group as compared to the LAU group showed subtle improvements in executive functions. Conclusions We observed DI-induced improvement in executive functions and increases of cortical thickness in the lateral occipitotemporal cortex which is engaged in action observation, visuomotor integration and action imitation, that is activities that are all important for motor learning and executing skilled movements.
ER  -

Basic information
Original name	Brain structure changes in nondemented seniors after six-month dance-exercise intervention
Authors	REKTOROVÁ, Irena (203 Czech Republic, belonging to the institution), Patrícia KLOBUŠIAKOVÁ (703 Slovakia, belonging to the institution), Zuzana BALÁŽOVÁ (703 Slovakia, belonging to the institution), Sylvie KROPÁČOVÁ (203 Czech Republic, belonging to the institution), Alžběta ŠEJNOHA MINSTEROVÁ (203 Czech Republic, belonging to the institution), Roman GRMELA (203 Czech Republic, belonging to the institution), Alena SKOTÁKOVÁ (203 Czech Republic, belonging to the institution) and Ivan REKTOR (203 Czech Republic, guarantor, belonging to the institution).
Edition	Acta Neurologica Scandinavica, Hoboken, WILEY-BLACKWELL, 2020, 0001-6314.

Other information
Original language	English
Type of outcome	Article in a journal
Field of Study	30210 Clinical neurology
Country of publisher	United States of America
Confidentiality degree	is not subject to a state or trade secret
WWW	URL
Impact factor	Impact factor: 3.209
RIV identification code	RIV/00216224:14740/20:00118391
Organization unit	Central European Institute of Technology
Doi	http://dx.doi.org/10.1111/ane.13181
UT WoS	000494532200001
Keywords in English	cognitive; cortical thickness; dance-exercise intervention; DTI; healthy seniors; lateral temporo-occipital cortex; mild cognitive impairment; MRI
Tags	14110127, podil, rivok
Tags	International impact, Reviewed
Changed by	Changed by: Mgr. Pavla Foltynová, Ph.D., učo 106624. Changed: 27/4/2021 19:01.

Abstract
Objectives To evaluate effects of a six-month intensive dance-exercise intervention (DI) on cognition and brain structure in a mixed group of healthy seniors and people with mild cognitive impairment. Methods Subjects (aged > 60 years with no dementia or depression) were randomly assigned to either a DI group or a life as usual (LAU) group. Detailed neuropsychological testing, measures of physical fitness and brain MRI encompassing T1 structural and diffusion tensor imaging (DTI) were performed at baseline and after 6 months. We assessed changes in cortical thickness and DTI parameters derived from tract-based spatial statistics. Results Altogether 62 individuals (n = 31 in the DI group) completed the protocol. The groups were matched for their demographic and clinical variables. After 6 months, we found significant cortical thickening in the right inferior temporal, fusiform and lateral occipital regions in the dancers compared to controls. Significant increases of radial and mean diffusivity were observed in various white matter tracts in the dancers; however, no differences were observed between the DI and LAU groups. The DI group as compared to the LAU group showed subtle improvements in executive functions. Conclusions We observed DI-induced improvement in executive functions and increases of cortical thickness in the lateral occipitotemporal cortex which is engaged in action observation, visuomotor integration and action imitation, that is activities that are all important for motor learning and executing skilled movements.

Abstract

Objectives To evaluate effects of a six-month intensive dance-exercise intervention (DI) on cognition and brain structure in a mixed group of healthy seniors and people with mild cognitive impairment. Methods Subjects (aged > 60 years with no dementia or depression) were randomly assigned to either a DI group or a life as usual (LAU) group. Detailed neuropsychological testing, measures of physical fitness and brain MRI encompassing T1 structural and diffusion tensor imaging (DTI) were performed at baseline and after 6 months. We assessed changes in cortical thickness and DTI parameters derived from tract-based spatial statistics. Results Altogether 62 individuals (n = 31 in the DI group) completed the protocol. The groups were matched for their demographic and clinical variables. After 6 months, we found significant cortical thickening in the right inferior temporal, fusiform and lateral occipital regions in the dancers compared to controls. Significant increases of radial and mean diffusivity were observed in various white matter tracts in the dancers; however, no differences were observed between the DI and LAU groups. The DI group as compared to the LAU group showed subtle improvements in executive functions. Conclusions We observed DI-induced improvement in executive functions and increases of cortical thickness in the lateral occipitotemporal cortex which is engaged in action observation, visuomotor integration and action imitation, that is activities that are all important for motor learning and executing skilled movements.

Links
EF16_013/0001775, research and development project	Name: Modernizace a podpora výzkumných aktivit národní infrastruktury pro biologické a medicínské zobrazování Czech-BioImaging
NV15-33854A, research and development project	Name: Efekt intenzivní tanečně-pohybové intervence na kognitivní funkce a změny mozkové plasticity zdravých seniorů a pacientů s mírnou kognitivní poruchou