HLUCHÝ, Milan, David POTĚŠIL, Zbyněk ZDRÁHAL and Dalibor BLAŽEK. Identification of CDK11 interactome. In CEITEC PhD Conference. 2020.
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Basic information
Original name Identification of CDK11 interactome
Authors HLUCHÝ, Milan (703 Slovakia, belonging to the institution), David POTĚŠIL (203 Czech Republic, belonging to the institution), Zbyněk ZDRÁHAL (203 Czech Republic, belonging to the institution) and Dalibor BLAŽEK (203 Czech Republic, belonging to the institution).
Edition CEITEC PhD Conference, 2020.
Other information
Original language English
Type of outcome Conference abstract
Field of Study 10608 Biochemistry and molecular biology
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
WWW URL
RIV identification code RIV/00216224:14740/20:00118404
Organization unit Central European Institute of Technology
Keywords in English Cdk11
Tags rivok
Changed by Changed by: Mgr. Pavla Foltynová, Ph.D., učo 106624. Changed: 5/1/2022 13:56.
Abstract
Cdk11 is a poorly-characterized cyclin-dependent kinase with described functions in transcription, alternative splicing and 3’end processing of HIV mRNA. Our aim was to better define its cellular roles via identification of its novel interacting partners and candidate substrates. We utilized BioID method and identified proteins implicated in control of gene expression. We utilized also Cdk11 analog-sensitive mutant to test the candidate interacting partners as substrates of Cdk11.
Links
LQ1601, research and development projectName: CEITEC 2020 (Acronym: CEITEC2020)
Investor: Ministry of Education, Youth and Sports of the CR
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