a 2020

Identification of CDK11 interactome

HLUCHÝ, Milan, David POTĚŠIL, Zbyněk ZDRÁHAL and Dalibor BLAŽEK

Basic information

Original name

Identification of CDK11 interactome

Authors

HLUCHÝ, Milan (703 Slovakia, belonging to the institution), David POTĚŠIL (203 Czech Republic, belonging to the institution), Zbyněk ZDRÁHAL (203 Czech Republic, belonging to the institution) and Dalibor BLAŽEK (203 Czech Republic, belonging to the institution)

Edition

CEITEC PhD Conference, 2020

Other information

Language

English

Type of outcome

Konferenční abstrakt

Field of Study

10608 Biochemistry and molecular biology

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

RIV identification code

RIV/00216224:14740/20:00118404

Organization unit

Central European Institute of Technology

Keywords in English

Cdk11

Tags

Změněno: 5/1/2022 13:56, Mgr. Pavla Foltynová, Ph.D.

Abstract

V originále

Cdk11 is a poorly-characterized cyclin-dependent kinase with described functions in transcription, alternative splicing and 3’end processing of HIV mRNA. Our aim was to better define its cellular roles via identification of its novel interacting partners and candidate substrates. We utilized BioID method and identified proteins implicated in control of gene expression. We utilized also Cdk11 analog-sensitive mutant to test the candidate interacting partners as substrates of Cdk11.

Links

LQ1601, research and development project
Name: CEITEC 2020 (Acronym: CEITEC2020)
Investor: Ministry of Education, Youth and Sports of the CR