J 2010

Use of the Crustacean Artemia franciscana for Alternative Biotests

DVORAK, Petr, Katarina BENOVA, Michal ZDARSKY, Zbynek SKLENAR, Alena HAVELKOVÁ et. al.

Basic information

Original name

Use of the Crustacean Artemia franciscana for Alternative Biotests

Authors

DVORAK, Petr, Katarina BENOVA, Michal ZDARSKY, Zbynek SKLENAR and Alena HAVELKOVÁ

Edition

Acta veterinaria (Brno), Brno, VFU Brno, ČR, 2010, 0001-7213

Other information

Type of outcome

Článek v odborném periodiku

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 0.534

Organization unit

Faculty of Medicine

DOI

UT WoS

000282195800008

Tags

Reviewed
Změněno: 25/3/2021 12:34, Mgr. Tereza Miškechová

Abstract

V originále

Use of the crustacean Artemia franciscana for alternative biotests of the second generation was studied, and possible experimental design and applications of such tests outlined. In addition to the classical use in ecotoxicology, the test can be used in pharmacology as well, or to monitor the effects of ionizing radiation in co-exposure with some chemical compounds. The synergistic effect of co-exposure of PCB (DELOR 103), cadmium chloride and potassium dichromate with beta (89)Sr irradiation was shown. We also demonstrated the anti-oxidative and pro-oxidative effects of the ascorbic acid in dependence on its concentration. Use of the pharmaco-toxicological screening in search for the novel inhibitors of cyclin-dependent kinases was demonstrated as well, showing that Artemia franciscana may be used as a suitable biosensor instead of the expensive tests on higher vertebrates.