DVORAK, Petr, Katarina BENOVA, Michal ZDARSKY, Zbynek SKLENAR and Alena HAVELKOVÁ. Use of the Crustacean Artemia franciscana for Alternative Biotests. Acta veterinaria (Brno). Brno: VFU Brno, ČR, 2010, vol. 79, p. "S47"-"S53". ISSN 0001-7213. Available from: https://dx.doi.org/10.2754/avb201079S9S047.
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Basic information
Original name Use of the Crustacean Artemia franciscana for Alternative Biotests
Authors DVORAK, Petr, Katarina BENOVA, Michal ZDARSKY, Zbynek SKLENAR and Alena HAVELKOVÁ.
Edition Acta veterinaria (Brno), Brno, VFU Brno, ČR, 2010, 0001-7213.
Other information
Type of outcome Article in a journal
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 0.534
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.2754/avb201079S9S047
UT WoS 000282195800008
Tags Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 25/3/2021 12:34.
Abstract
Use of the crustacean Artemia franciscana for alternative biotests of the second generation was studied, and possible experimental design and applications of such tests outlined. In addition to the classical use in ecotoxicology, the test can be used in pharmacology as well, or to monitor the effects of ionizing radiation in co-exposure with some chemical compounds. The synergistic effect of co-exposure of PCB (DELOR 103), cadmium chloride and potassium dichromate with beta (89)Sr irradiation was shown. We also demonstrated the anti-oxidative and pro-oxidative effects of the ascorbic acid in dependence on its concentration. Use of the pharmaco-toxicological screening in search for the novel inhibitors of cyclin-dependent kinases was demonstrated as well, showing that Artemia franciscana may be used as a suitable biosensor instead of the expensive tests on higher vertebrates.
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