Detailed Information on Publication Record
2021
Prevalence of COVID-19 Vaccine Side Effects among Healthcare Workers in the Czech Republic
RIAD, Abanoub, Andrea POKORNÁ, Sameh ATTIA, Jitka KLUGAROVÁ, Michal KOŠČÍK et. al.Basic information
Original name
Prevalence of COVID-19 Vaccine Side Effects among Healthcare Workers in the Czech Republic
Authors
RIAD, Abanoub (818 Egypt, guarantor, belonging to the institution), Andrea POKORNÁ (203 Czech Republic, belonging to the institution), Sameh ATTIA, Jitka KLUGAROVÁ (203 Czech Republic, belonging to the institution), Michal KOŠČÍK (203 Czech Republic, belonging to the institution) and Miloslav KLUGAR (203 Czech Republic, belonging to the institution)
Edition
Journal of Clinical Medicine, Basel, MDPI, 2021, 2077-0383
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30218 General and internal medicine
Country of publisher
Switzerland
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
Impact factor
Impact factor: 4.964
RIV identification code
RIV/00216224:14110/21:00121325
Organization unit
Faculty of Medicine
UT WoS
000638607800001
Keywords in English
adverse effects; BNT162 vaccine; cross-sectional studies; COVID-19; Czech Republic; drug-related side effects and adverse reactions; health personnel; mass vaccination; prevalence
Tags
International impact, Reviewed
Změněno: 17/5/2022 08:58, Mgr. Tereza Miškechová
Abstract
V originále
Background: COVID-19 vaccine side effects have a fundamental role in public confidence in the vaccine and its uptake process. Thus far, the evidence on vaccine safety has exclusively been obtained from the manufacturer-sponsored studies; therefore, this study was designed to provide independent evidence on Pfizer–BioNTech COVID-19 vaccine side effects. Methods: A cross-sectional survey-based study was carried out between January and February 2021 to collect data on the side effects following the COVID-19 vaccine among healthcare workers in the Czech Republic. The study used a validated questionnaire with twenty-eight multiple-choice items covering the participants’ demographic data, medical anamneses, COVID-19-related anamneses, general, oral, and skin-related side effects. Results: Injection site pain (89.8%), fatigue (62.2%), headache (45.6%), muscle pain (37.1%), and chills (33.9%) were the most commonly reported side effects. All the general side effects were more prevalent among the ≤43-year-old group, and their duration was mainly one day (45.1%) or three days (35.8%) following the vaccine. Antihistamines were the most common drugs associated with side effects, thus requiring further investigation. The people with two doses were generally associated with a higher frequency of side effects. Conclusions: The distribution of side effects among Czech healthcare workers was highly consistent with the manufacturer’s data, especially in terms of their association with the younger age group and the second dose. The overall prevalence of some local and systemic side effects was higher than the manufacturer’s report. Further independent studies on vaccine safety are strongly required to strengthen public confidence in the vaccine.
Links
| CZ.02.1.01/0.0/0.0/16_013/0001826, interní kód MU (CEP code: EF16_013/0001826) |
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| LTC20031, research and development project |
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| MUNI/A/1608/2020, interní kód MU |
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| MUNI/IGA/1543/2020, interní kód MU |
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| 90128, large research infrastructures |
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