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@article{1758064,
author = {Šiška, Filip and Amchová, Petra and Kuruczová, Daniela and Tizabi, Yousef and Rudá, Jana},
article_location = {Oxon},
article_number = {10},
doi = {http://dx.doi.org/10.1080/15622975.2021.1907717},
keywords = {Alcohol use disorder; AMPA/kainate receptor; Depression; NBQX; Olfactory bulbectomy; Rats},
language = {eng},
issn = {1562-2975},
journal = {The World Journal of Biological Psychiatry},
title = {Effects of low-dose alcohol exposure in adolescence on subsequent alcohol drinking in adulthood in a rat model of depression},
url = {https://www.tandfonline.com/doi/full/10.1080/15622975.2021.1907717},
volume = {22},
year = {2021}
}
TY - JOUR
ID - 1758064
AU - Šiška, Filip - Amchová, Petra - Kuruczová, Daniela - Tizabi, Yousef - Rudá, Jana
PY - 2021
TI - Effects of low-dose alcohol exposure in adolescence on subsequent alcohol drinking in adulthood in a rat model of depression
JF - The World Journal of Biological Psychiatry
VL - 22
IS - 10
SP - 757-769
EP - 757-769
PB - TAYLOR & FRANCIS
SN - 15622975
KW - Alcohol use disorder
KW - AMPA/kainate receptor
KW - Depression
KW - NBQX
KW - Olfactory bulbectomy
KW - Rats
UR - https://www.tandfonline.com/doi/full/10.1080/15622975.2021.1907717
N2 - Adolescence drinking and subsequent development of alcohol use disorder (AUD) is a worldwide health concern. In particular, mood dysregulation or early alcohol exposure can be the cause of heavy drinking in some individuals or a consequence of heavy drinking in others. This study investigated the effects of voluntary alcohol intake during adolescence, i.e. continuous 10% alcohol access between postnatal days (PND) 29 to 43 and olfactory bulbectomy (OBX) model of depression (performed on PND 59) on alcohol drinking in Wistar rats during adulthood (PND 80-120, intermittent 20% alcohol access). In addition, the effect of NBQX, an AMPA/kainate receptor antagonist (5 mg/kg, IP) on spontaneous alcohol consumption was examined.
ER -
ŠIŠKA, Filip, Petra AMCHOVÁ, Daniela KURUCZOVÁ, Yousef TIZABI and Jana RUDÁ. Effects of low-dose alcohol exposure in adolescence on subsequent alcohol drinking in adulthood in a rat model of depression. \textit{The World Journal of Biological Psychiatry}. Oxon: TAYLOR \&{} FRANCIS, 2021, vol.~22, No~10, p.~757-769. ISSN~1562-2975. Available from: https://dx.doi.org/10.1080/15622975.2021.1907717.
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