On the limits of finite element models created from (micro)CT
datasets and used in studies of bone-implant-related
biomechanical problems

J 2021

On the limits of finite element models created from (micro)CT datasets and used in studies of bone-implant-related biomechanical problems

MARCIAN, Petr, Libor BORAK, Tomas ZIKMUND, Ladislava HORÁČKOVÁ, Jozef KAISER et. al.

Basic information

Original name

On the limits of finite element models created from (micro)CT datasets and used in studies of bone-implant-related biomechanical problems

Authors

MARCIAN, Petr (203 Czech Republic), Libor BORAK (203 Czech Republic, guarantor), Tomas ZIKMUND (203 Czech Republic), Ladislava HORÁČKOVÁ (203 Czech Republic, belonging to the institution), Jozef KAISER, Marek JOUKAL (203 Czech Republic, belonging to the institution) and Jan WOLFF (276 Germany)

Edition

Journal of the Mechanical Behavior of Biomedical Materials, Elsevier, Amsterdam, 2021, 1751-6161

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30404 Biomaterials

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 4.042

RIV identification code

RIV/00216224:14110/21:00121433

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1016/j.jmbbm.2021.104393

UT WoS

000635269700003

Keywords in English

Finite element method; Computational modeling; Computed tomography; Image resolution; Bone tissue; Mechanical strain

Abstract

V originále

Patient-specific approach is gaining a wide popularity in computational simulations of biomechanical systems. Simulations (most often based on the finite element method) are to date routinely created using data from imaging devices such as computed tomography which makes the models seemingly very complex and sophisticated. However, using a computed tomography in finite element calculations does not necessarily enhance the quality or even credibility of the models as these depend on the quality of the input images. Low-resolution (medical-)CT datasets do not always offer detailed representation of trabecular bone in FE models and thus might lead to incorrect calculation of mechanical response to external loading. The effect of image resolution on mechanical simulations of bone-implant interaction has not been thoroughly studied yet. In this study, the effect of image resolution on the modeling procedure and resulting mechanical strains in bone was analyzed on the example of cranial implant. For this purpose, several finite element models of bone interacting with fixationscrews were generated using seven computed tomography datasets of a bone specimen but with different image resolutions (ranging from micro-CT resolution of 25 ?m to medical-CT resolution of 1250 ?m). The comparative analysis revealed that FE models created from images of low resolution (obtained from medical computed tomography) can produce biased results. There are two main reasons: 1. Medical computed tomography images do not allow generating models with complex trabecular architecture which leads to substituting of the intertrabecular pores with a fictitious mass; 2. Image gray value distribution can be distorted resulting in incorrect mechanical properties of the bone and thus in unrealistic or even completely fictitious mechanical strains. The biased results of calculated mechanical strains can lead to incorrect conclusion, especially when bone-implant interaction is investigated. The image resolution was observed not to significantly affect stresses in the fixation screw itself; however, selection of bone material representation might result in significantly different stresses in the screw.

Links

LQ1601, research and development project

Name: CEITEC 2020 (Acronym: CEITEC2020)

Investor: Ministry of Education, Youth and Sports of the CR

90110, large research infrastructures

Name: CzechNanoLab

Citovat

MARCIAN, Petr, Libor BORAK, Tomas ZIKMUND, Ladislava HORÁČKOVÁ, Jozef KAISER, Marek JOUKAL and Jan WOLFF. On the limits of finite element models created from (micro)CT datasets and used in studies of bone-implant-related biomechanical problems. Journal of the Mechanical Behavior of Biomedical Materials. Elsevier: Amsterdam, 2021, vol. 117, MAY 2021, p. 1-13. ISSN 1751-6161. Available from: https://dx.doi.org/10.1016/j.jmbbm.2021.104393.

@article{1761857,
   author = {Marcian, Petr and Borak, Libor and Zikmund, Tomas and Horáčková, Ladislava and Kaiser, Jozef and Joukal, Marek and Wolff, Jan},
   article_location = {Elsevier},
   article_number = {MAY 2021},
   doi = {http://dx.doi.org/10.1016/j.jmbbm.2021.104393},
   keywords = {Finite element method; Computational modeling; Computed tomography; Image resolution; Bone tissue; Mechanical strain},
   language = {eng},
   issn = {1751-6161},
   journal = {Journal of the Mechanical Behavior of Biomedical Materials},
   title = {On the limits of finite element models created from (micro)CT datasets and used in studies of bone-implant-related biomechanical problems},
   url = {https://www.sciencedirect.com/science/article/pii/S1751616121000825?via%3Dihub},
   volume = {117},
   year = {2021}
}

TY  - JOUR
ID  - 1761857
AU  - Marcian, Petr - Borak, Libor - Zikmund, Tomas - Horáčková, Ladislava - Kaiser, Jozef - Joukal, Marek - Wolff, Jan
PY  - 2021
TI  - On the limits of finite element models created from (micro)CT datasets and used in studies of bone-implant-related biomechanical problems
JF  - Journal of the Mechanical Behavior of Biomedical Materials
VL  - 117
IS  - MAY 2021
SP  - 1-13
EP  - 1-13
PB  - Amsterdam
SN  - 17516161
KW  - Finite element method
KW  - Computational modeling
KW  - Computed tomography
KW  - Image resolution
KW  - Bone tissue
KW  - Mechanical strain
UR  - https://www.sciencedirect.com/science/article/pii/S1751616121000825?via%3Dihub
N2  - Patient-specific approach is gaining a wide popularity in computational simulations of biomechanical systems. Simulations (most often based on the finite element method) are to date routinely created using data from imaging devices such as computed tomography which makes the models seemingly very complex and sophisticated. However, using a computed tomography in finite element calculations does not necessarily enhance the quality or even credibility of the models as these depend on the quality of the input images. Low-resolution (medical-)CT datasets do not always offer detailed representation of trabecular bone in FE models and thus might lead to incorrect calculation of mechanical response to external loading. The effect of image resolution on mechanical simulations of bone-implant interaction has not been thoroughly studied yet. In this study, the effect of image resolution on the modeling procedure and resulting mechanical strains in bone was analyzed on the example of cranial implant. For this purpose, several finite element models of bone interacting with fixationscrews were generated using seven computed tomography datasets of a bone specimen but with different image resolutions (ranging from micro-CT resolution of 25 ?m to medical-CT resolution of 1250 ?m). The comparative analysis revealed that FE models created from images of low resolution (obtained from medical computed tomography) can produce biased results. There are two main reasons: 1. Medical computed tomography images do not allow generating models with complex trabecular architecture which leads to substituting of the intertrabecular pores with a fictitious mass; 2. Image gray value distribution can be distorted resulting in incorrect mechanical properties of the bone and thus in unrealistic or even completely fictitious mechanical strains. The biased results of calculated mechanical strains can lead to incorrect conclusion, especially when bone-implant interaction is investigated. The image resolution was observed not to significantly affect stresses in the fixation screw itself; however, selection of bone material representation might result in significantly different stresses in the screw.
ER  -

MARCIAN, Petr, Libor BORAK, Tomas ZIKMUND, Ladislava HORÁČKOVÁ, Jozef KAISER, Marek JOUKAL and Jan WOLFF. On the limits of finite element models created from (micro)CT datasets and used in studies of bone-implant-related biomechanical problems. \textit{Journal of the Mechanical Behavior of Biomedical Materials}. Elsevier: Amsterdam, 2021, vol.~117, MAY 2021, p.~1-13. ISSN~1751-6161. Available from: https://dx.doi.org/10.1016/j.jmbbm.2021.104393.

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