Effect of Acupuncture in Pain Management of Head and Neck
Cancer Radiotherapy: Prospective Randomized Unicentric Study

J 2021

Effect of Acupuncture in Pain Management of Head and Neck Cancer Radiotherapy: Prospective Randomized Unicentric Study

DYMÁČKOVÁ, Radana, Iveta SELINGEROVÁ, Tomáš KAZDA, Marek SLÁVIK, Jana HALÁMKOVÁ et. al.

Basic information

Original name

Effect of Acupuncture in Pain Management of Head and Neck Cancer Radiotherapy: Prospective Randomized Unicentric Study

Authors

DYMÁČKOVÁ, Radana (203 Czech Republic, guarantor, belonging to the institution), Iveta SELINGEROVÁ (203 Czech Republic), Tomáš KAZDA (203 Czech Republic), Marek SLÁVIK (703 Slovakia, belonging to the institution), Jana HALÁMKOVÁ (203 Czech Republic, belonging to the institution), Michaela ŠVAJDOVÁ (703 Slovakia, belonging to the institution), Pavel ŠLAMPA (203 Czech Republic) and Ondřej SLÁMA (203 Czech Republic)

Edition

Journal of Clinical Medicine, Basel, MDPI, 2021, 2077-0383

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30218 General and internal medicine

Country of publisher

Switzerland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 4.964

RIV identification code

RIV/00216224:14110/21:00121459

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.3390/jcm10051111

UT WoS

000628269300001

Keywords (in Czech)

akupunktura, nádory hlavy a krku, radioterapie, toxicita, bolest

Keywords in English

acupuncture; head and neck cancer; radiotherapy; toxicity; pain

Abstract

V originále

This prospective randomized open-label trial aimed to evaluate the role of acupuncture in the treatment of pain related to curative and adjuvant (chemo)radiotherapy of head and neck cancer. Patients in two arms (30 patients in each arm) underwent standard oncology therapy and standard supportive care with or without acupuncture. The stratification factors were the type of treatment and chemotherapy indication. The toxicity assessed was represented by pain rated on a 10-point pain scale and analgesic use. Average pain (AP) and the worst pain during the day (WP) were significantly lower in the acupuncture arm during radiotherapy (AP median 0.16 vs. 1.36, p < 0.001; WP median 0.90 vs. 1.96, p < 0.001) and three months after radiotherapy (AP median 0.07 vs. 0.50, p < 0.001; WP median 0.30 vs. 0.83, p = 0.002). The analgesic consumption between arms was statistically significantly different. A median of the proportion of days when the patients used analgesics was 8% and 32.5% during radiotherapy (p = 0.047) and 0% and 20.8% during three months after radiotherapy (p = 0.006) for the acupuncture and control arm, respectively. Results point out lower analgesic consumption and milder pain in acupuncture arm. Acupuncture consequently offers another alternative to standard treatment leading to a reduction in the toxicity of oncological treatment.

Citovat

DYMÁČKOVÁ, Radana, Iveta SELINGEROVÁ, Tomáš KAZDA, Marek SLÁVIK, Jana HALÁMKOVÁ, Michaela ŠVAJDOVÁ, Pavel ŠLAMPA and Ondřej SLÁMA. Effect of Acupuncture in Pain Management of Head and Neck Cancer Radiotherapy: Prospective Randomized Unicentric Study. Journal of Clinical Medicine. Basel: MDPI, 2021, vol. 10, No 5, p. 1-12. ISSN 2077-0383. Available from: https://dx.doi.org/10.3390/jcm10051111.

@article{1762737,
   author = {Dymáčková, Radana and Selingerová, Iveta and Kazda, Tomáš and Slávik, Marek and Halámková, Jana and Švajdová, Michaela and Šlampa, Pavel and Sláma, Ondřej},
   article_location = {Basel},
   article_number = {5},
   doi = {http://dx.doi.org/10.3390/jcm10051111},
   keywords = {acupuncture; head and neck cancer; radiotherapy; toxicity; pain},
   language = {eng},
   issn = {2077-0383},
   journal = {Journal of Clinical Medicine},
   title = {Effect of Acupuncture in Pain Management of Head and Neck Cancer Radiotherapy: Prospective Randomized Unicentric Study},
   url = {https://www.mdpi.com/2077-0383/10/5/1111},
   volume = {10},
   year = {2021}
}

TY  - JOUR
ID  - 1762737
AU  - Dymáčková, Radana - Selingerová, Iveta - Kazda, Tomáš - Slávik, Marek - Halámková, Jana - Švajdová, Michaela - Šlampa, Pavel - Sláma, Ondřej
PY  - 2021
TI  - Effect of Acupuncture in Pain Management of Head and Neck Cancer Radiotherapy: Prospective Randomized Unicentric Study
JF  - Journal of Clinical Medicine
VL  - 10
IS  - 5
SP  - 1-12
EP  - 1-12
PB  - MDPI
SN  - 20770383
KW  - acupuncture
KW  - head and neck cancer
KW  - radiotherapy
KW  - toxicity
KW  - pain
UR  - https://www.mdpi.com/2077-0383/10/5/1111
N2  - This prospective randomized open-label trial aimed to evaluate the role of acupuncture in the treatment of pain related to curative and adjuvant (chemo)radiotherapy of head and neck cancer. Patients in two arms (30 patients in each arm) underwent standard oncology therapy and standard supportive care with or without acupuncture. The stratification factors were the type of treatment and chemotherapy indication. The toxicity assessed was represented by pain rated on a 10-point pain scale and analgesic use. Average pain (AP) and the worst pain during the day (WP) were significantly lower in the acupuncture arm during radiotherapy (AP median 0.16 vs. 1.36, p < 0.001; WP median 0.90 vs. 1.96, p < 0.001) and three months after radiotherapy (AP median 0.07 vs. 0.50, p < 0.001; WP median 0.30 vs. 0.83, p = 0.002). The analgesic consumption between arms was statistically significantly different. A median of the proportion of days when the patients used analgesics was 8% and 32.5% during radiotherapy (p = 0.047) and 0% and 20.8% during three months after radiotherapy (p = 0.006) for the acupuncture and control arm, respectively. Results point out lower analgesic consumption and milder pain in acupuncture arm. Acupuncture consequently offers another alternative to standard treatment leading to a reduction in the toxicity of oncological treatment.
ER  -

DYMÁČKOVÁ, Radana, Iveta SELINGEROVÁ, Tomáš KAZDA, Marek SLÁVIK, Jana HALÁMKOVÁ, Michaela ŠVAJDOVÁ, Pavel ŠLAMPA and Ondřej SLÁMA. Effect of Acupuncture in Pain Management of Head and Neck Cancer Radiotherapy: Prospective Randomized Unicentric Study. \textit{Journal of Clinical Medicine}. Basel: MDPI, 2021, vol.~10, No~5, p.~1-12. ISSN~2077-0383. Available from: https://dx.doi.org/10.3390/jcm10051111.

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