DYMÁČKOVÁ, Radana, Iveta SELINGEROVÁ, Tomáš KAZDA, Marek SLÁVIK, Jana HALÁMKOVÁ, Michaela ŠVAJDOVÁ, Pavel ŠLAMPA and Ondřej SLÁMA. Effect of Acupuncture in Pain Management of Head and Neck Cancer Radiotherapy: Prospective Randomized Unicentric Study. Journal of Clinical Medicine. Basel: MDPI, 2021, vol. 10, No 5, p. 1-12. ISSN 2077-0383. Available from: https://dx.doi.org/10.3390/jcm10051111.
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Basic information
Original name Effect of Acupuncture in Pain Management of Head and Neck Cancer Radiotherapy: Prospective Randomized Unicentric Study
Authors DYMÁČKOVÁ, Radana (203 Czech Republic, guarantor, belonging to the institution), Iveta SELINGEROVÁ (203 Czech Republic), Tomáš KAZDA (203 Czech Republic), Marek SLÁVIK (703 Slovakia, belonging to the institution), Jana HALÁMKOVÁ (203 Czech Republic, belonging to the institution), Michaela ŠVAJDOVÁ (703 Slovakia, belonging to the institution), Pavel ŠLAMPA (203 Czech Republic) and Ondřej SLÁMA (203 Czech Republic).
Edition Journal of Clinical Medicine, Basel, MDPI, 2021, 2077-0383.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30218 General and internal medicine
Country of publisher Switzerland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 4.964
RIV identification code RIV/00216224:14110/21:00121459
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.3390/jcm10051111
UT WoS 000628269300001
Keywords (in Czech) akupunktura, nádory hlavy a krku, radioterapie, toxicita, bolest
Keywords in English acupuncture; head and neck cancer; radiotherapy; toxicity; pain
Tags 14110811, 14110812, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 17/5/2022 09:03.
Abstract
This prospective randomized open-label trial aimed to evaluate the role of acupuncture in the treatment of pain related to curative and adjuvant (chemo)radiotherapy of head and neck cancer. Patients in two arms (30 patients in each arm) underwent standard oncology therapy and standard supportive care with or without acupuncture. The stratification factors were the type of treatment and chemotherapy indication. The toxicity assessed was represented by pain rated on a 10-point pain scale and analgesic use. Average pain (AP) and the worst pain during the day (WP) were significantly lower in the acupuncture arm during radiotherapy (AP median 0.16 vs. 1.36, p < 0.001; WP median 0.90 vs. 1.96, p < 0.001) and three months after radiotherapy (AP median 0.07 vs. 0.50, p < 0.001; WP median 0.30 vs. 0.83, p = 0.002). The analgesic consumption between arms was statistically significantly different. A median of the proportion of days when the patients used analgesics was 8% and 32.5% during radiotherapy (p = 0.047) and 0% and 20.8% during three months after radiotherapy (p = 0.006) for the acupuncture and control arm, respectively. Results point out lower analgesic consumption and milder pain in acupuncture arm. Acupuncture consequently offers another alternative to standard treatment leading to a reduction in the toxicity of oncological treatment.
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