J 2021

Pathogenesis of Retraction Pocket of the Tympanic Membrane - A Narrative Review

URÍK, Milan, Miroslav TEDLA and Pavel HURNÍK

Basic information

Original name

Pathogenesis of Retraction Pocket of the Tympanic Membrane - A Narrative Review

Authors

URÍK, Milan (703 Slovakia, belonging to the institution), Miroslav TEDLA (703 Slovakia) and Pavel HURNÍK (203 Czech Republic, guarantor)

Edition

Medicina, Basel, MDPI, 2021, 1010-660X

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30218 General and internal medicine

Country of publisher

Switzerland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 2.948

RIV identification code

RIV/00216224:14110/21:00120093

Organization unit

Faculty of Medicine

UT WoS

000654307200001

Keywords in English

retraction pocket; tympanic membrane; pathogenesis; pathology; chronic otitis media; cholesteatoma

Tags

Tags

International impact, Reviewed
Změněno: 20/5/2022 13:30, Mgr. Tereza Miškechová

Abstract

V originále

Several theories describe the development of the retraction pocket of the tympanic membrane (RP). Many authors suggest that the negative middle ear pressure is the main reason responsible for developing this condition. A narrative review has been undertaken, and conclusions are drawn reflecting a current knowledge with our new observations in the histological and immunohistochemical study. Recent studies show the important role of inflammation in the development and progression of RP. A review of the available literature shows that the inflammation plays a key role in pathogenesis of the RP and its progression to the cholesteatoma. We support this statement with our new results from histological and immunohistochemical analysis of the RPs.

Links

MUNI/A/1118/2020, interní kód MU
Name: Ztráta sluchu v dětském věku - příčiny, diagnostika, možnosti rehabilitace V.
Investor: Masaryk University
NU20-08-00205, research and development project
Name: Molekulární etiopatogeneze apikální periodontitidy a odontogenních cyst
Investor: Ministry of Health of the CR, Subprogram 1 - standard