MIKULÍK, Robert, Michal BAR, David CERNIK, Roman HERZIG, René JURA, Lubomir JURAK, Jiri NEUMANN, Daniel SANAK, Svatopluk OSTRY, Petr SEVCIK, Ondrej SKODA, David SKOLOUDIK, Daniel VACLAVIK and Ales TOMEK. Stroke 20 20: Implementation goals for intravenous thrombolysis. EUROPEAN STROKE JOURNAL. LONDON: SAGE PUBLICATIONS LTD, 2021, vol. 6, No 2, p. 151-159. ISSN 2396-9873. Available from: https://dx.doi.org/10.1177/23969873211007684.
Other formats:   BibTeX LaTeX RIS
Basic information
Original name Stroke 20 20: Implementation goals for intravenous thrombolysis
Authors MIKULÍK, Robert (203 Czech Republic, guarantor, belonging to the institution), Michal BAR (203 Czech Republic), David CERNIK (203 Czech Republic), Roman HERZIG (203 Czech Republic), René JURA (203 Czech Republic, belonging to the institution), Lubomir JURAK (203 Czech Republic), Jiri NEUMANN (203 Czech Republic), Daniel SANAK (203 Czech Republic), Svatopluk OSTRY (203 Czech Republic), Petr SEVCIK (203 Czech Republic), Ondrej SKODA (203 Czech Republic), David SKOLOUDIK (203 Czech Republic), Daniel VACLAVIK (203 Czech Republic) and Ales TOMEK (203 Czech Republic).
Edition EUROPEAN STROKE JOURNAL, LONDON, SAGE PUBLICATIONS LTD, 2021, 2396-9873.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30210 Clinical neurology
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 5.894
RIV identification code RIV/00216224:14110/21:00121597
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1177/23969873211007684
UT WoS 000641919100001
Keywords in English Thrombolytic rate; stroke care management; implementation of thrombolysis; acute stroke care
Tags 14110127, 14110221, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 8/2/2022 10:29.
Abstract
Introduction Knowledge of the implementation gap would facilitate the use of intravenous thrombolysis in stroke, which is still low in many countries. The study was conducted to identify national implementation targets for the utilisation and logistics of intravenous thrombolysis. Material and Method Multicomponent interventions by stakeholders in health care to optimise prehospital and hospital management with the goal of fast and accessible intravenous thrombolysis for every candidate. Implementation results were documented from prospectively collected cases in all 45 stroke centres nationally. The thrombolytic rate was calculated from the total number of all ischemic strokes in the population of the Czech Republic since 2004. Results Thrombolytic rates of 1.3 (95%CI 1.1 to 1.4), 5.4 (95%CI 5.1 to 5.7), 13.6 (95%CI 13.1 to 14.0), 23.3 (95%CI 22.8 to 23.9), and 23.5% (95%CI 23.0 to 24.1%) were achieved in 2005, 2009, 2014, 2017, and 2018, respectively. National median door-to-needle times were 60-70 minutes before 2012 and then decreased progressively every year to 25 minutes (IQR 17 to 36) in 2018. In 2018, 33% of both university and non-university hospitals achieved median door-to-needle time <= 20 minutes. In 2018, door-to-needle times <= 20, <= 45, and <= 60 minutes were achieved in 39, 85, and 93% of patients. Discussion Thrombolysis can be provided to >= 20% of all ischemic strokes nationwide and it is realistic to achieve median door-to-needle time 20 minutes. Conclusion Stroke 20-20 could serve as national implementation target for intravenous thrombolysis and country specific implementation policies should be applied to achieve such target.
Links
90128, large research infrastructuresName: CZECRIN III
PrintDisplayed: 27/4/2024 00:58